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How to get fromMinneapolis–Saint Paul to Cape Girardeauby plane, taxi, train, bus (Greyhound), car, bus, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Minneapolis–Saint Paul to Cape Girardeau by plane, taxi, train, bus (Greyhound), car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, taxi

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Barkley Regional Airport (PAH)plane plane MSP - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    8h 11m
    $224–624

  2. Drive 627.3 mi

    cheapest
    1. Drive from Minneapolis–Saint Paul to Cape Girardeaucar car 627.3 mi
    11h 20m
    $115–166

  3. Train, taxi

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    16h 29m
    $317–612

  4. Bus (Greyhound)

    1. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    19h 29m
    $121–236

  5. Fly to Lambert–St. Louis International Airport, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 59m
    $411–1,001

  6. Fly to Cape Girardeau Municipal Airport

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Cape Girardeau Municipal Airport (CGI)plane plane MSP - CGI
    6h 40m
    $157–682

  7. Fly to Memphis, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Memphis (MEM)plane plane MSP - MEM
    2. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    9h 28m
    $178–869

  8. Fly to Williamson County Regional Airport, taxi

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Williamson County Regional Airport (MWA)plane plane MSP - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    6h 50m
    $514–864

  9. Train, bus

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    17h 57m
    $231–506

  10. Bus via Chicago

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    22h 26m
    $157–286

Minneapolis–Saint Paul International Airport (MSP) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration5h 45mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis–Saint Paul to Cape Girardeau.ExpandLaunch map view
  • Distance: 660.7 mi
  • Duration: 8h 11m

What companies run services between Minneapolis–Saint Paul, MN, USA and Cape Girardeau, MO, USA?

You can take a bus from Marshall & Otis Station to Cape Girardeau via Union Depot Station & Terminal, Saint Paul Union Depot, Des Moines, St Louis Bus Station, and Cape Girardeau in around 19h 29m. Alternatively, American Airlines and Corporate Flight Management Inc fly from Minneapolis–Saint Paul International Airport (MSP) to Cape Girardeau Municipal Airport (CGI) twice daily.

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