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How to get fromMinneapolis–Saint Paul to Mayo Clinicby bus or car

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There are 3 ways to get from Minneapolis–Saint Paul to Mayo Clinic by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Marshall & Otis Station to Union Depot Station & Terminalbus bus METRO B Line
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    3h 3m
    $30–42

  2. Drive 80.7 mi

    cheapest
    1. Drive from Minneapolis–Saint Paul to Mayo Cliniccar car 80.7 mi
    1h 34m
    $15–22

  3. Bus, line 54 bus

    1. Take the bus from Marshall & Otis Station to Union Depot & Wacouta Stationbus bus
    2. Take the bus from Union Depot & Sibley Station to MSP Terminal 1 Transit Stationbus bus 54
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    4h 18m
    $54–56

Minneapolis–Saint Paul to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration3h 3mAverage Duration
Ticket$30Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis–Saint Paul to Mayo Clinic.ExpandLaunch map view
  • Distance: 84 mi
  • Duration: 3h 3m

What companies run services between Minneapolis–Saint Paul, MN, USA and Mayo Clinic, MN, USA?

You can take a bus from Marshall & Otis Station to Mayo Clinic via Union Depot Station & Terminal, St. Paul, and Rochester in around 3h 3m.

Operators

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