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How to get fromMinneapolis–Saint Paul to St. Louisby plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

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There are 5 ways to get from Minneapolis–Saint Paul to St. Louis by plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    3h 38m
    $387–958

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Saint Paul Union Depot to Des Moinesbus bus Greyhound US0156
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    16h 19m
    $97–192

  3. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    14h 45m
    $222–462

  4. Drive 528.6 mi

    1. Drive from Minneapolis–Saint Paul to St. Louiscar car 528.6 mi
    9h 40m
    $97–140

  5. Bus via Chicago

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    19h 17m
    $138–247

Minneapolis–Saint Paul to St. Louis by tram and train (Amtrak)

Calendar21Weekly Services
Duration14h 45mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis–Saint Paul to St. Louis.ExpandLaunch map view
  • Distance: 467.9 mi
  • Duration: 3h 38m

What companies run services between Minneapolis–Saint Paul, MN, USA and St. Louis, MO, USA?

Delta and Southwest Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a vehicle from Raymond Ave Station to St. Louis via Union Depot Station, St. Paul-Minneapolis, and Chicago Union Station in around 14h 45m.

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Need to know: Greyhound

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