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How to get fromMinneapolis to Louisvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Amtrak)

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There are 6 ways to get from Minneapolis to Louisville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    4h 24m
    $113–605

  2. Bus

    1. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus FlixBus 2548 / ...
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    16h 35m
    $117–227

  3. Train, bus

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    17h 39m
    $214–452

  4. Drive 701.2 mi

    1. Drive from Minneapolis to Louisvillecar car 701.2 mi
    11h 44m
    $128–185

  5. Fly to Blue Grass Airport, drive

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Blue Grass Airport (LEX)plane plane MSP - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 34m
    $185–971

  6. Bus via Madison

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus
    4. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus
    20h 6m
    $139–253

Minneapolis to Louisville by bus

Calendar63Weekly Buses
Duration16h 35mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis to Louisville.ExpandLaunch map view
  • Distance: 615.5 mi
  • Duration: 4h 24m

What companies run services between Minneapolis, MN, USA and Louisville, KY, USA?

Delta, Southwest Airlines, and United Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Minneapolis Bus Station to Louisville Bus Station via Chicago Bus Station in around 16h 35m.

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