There are 6 ways to get from Minneapolis to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), train, bus, car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane MSP - SDF
4h 27m$143–855Fly to Blue Grass Airport, drive
cheapest- Fly from Minneapolis–Saint Paul International Airport (MSP) to Blue Grass Airport (LEX)plane MSP - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
4h 34m$100–501Bus
- Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus Greyhound US0150
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
16h 24m$114–169Train, bus (Amtrak)
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
17h 44m$344–568Drive 701.2 mi
- Drive from Minneapolis to Louisvillecar 701.2 mi
11h 44m$128–185Bus via Madison
- Take the bus from Minneapolis to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Louisville, KYbus
18h 41m$136–218
Minneapolis to Louisville by bus and foot
Comparing Your Travel Options
The cheapest way to get from Minneapolis to Louisville is to bus which costs $110 - $170 and takes 16h 24m.
The fastest way to get from Minneapolis to Louisville is to fly which takes 4h 27m and costs $140 - $900.
No, there is no direct bus from Minneapolis station to Louisville. However, there are services departing from Minneapolis Bus Station and arriving at Louisville, KY via Chicago Union Station. The journey, including transfers, takes approximately 16h 24m.
The distance between Minneapolis and Louisville is 619 miles. The road distance is 705.3 miles.
The best way to get from Minneapolis to Louisville without a car is to bus which takes 16h 24m and costs $110 - $170.
It takes approximately 4h 27m to get from Minneapolis to Louisville, including transfers.
Minneapolis to Louisville bus services, operated by Greyhound USA, depart from Minneapolis Bus Station.
The best way to get from Minneapolis to Louisville is to fly which takes 4h 27m and costs $140 - $900. Alternatively, you can bus, which costs $110 - $170 and takes 16h 24m.
Minneapolis to Louisville bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Louisville is 1h ahead of Minneapolis. It is currently 2:14 AM in Minneapolis and 3:14 AM in Louisville.
What companies run services between Minneapolis, MN, USA and Louisville, KY, USA?
Delta, Southwest Airlines, and two other airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Minneapolis Bus Station to Louisville, KY via Chicago Bus Station and Chicago Union Station in around 16h 24m.
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 4m
- When
- Tuesday to Saturday
- Estimated price
- $140–850
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–950
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $140–850
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Minneapolis–Saint Paul International Airport to Blue Grass Airport
- Ave. Duration
- 1h 56m
- When
- Saturday
- Estimated price
- $85–480
- Website
- aa.com
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $140–850
Flights from Minneapolis–Saint Paul International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $85–490
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $140–850
Flights from Minneapolis–Saint Paul International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $85–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Minneapolis to Madison
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
- Phone
- +1 414-266-4409
- [email protected]
- Website
- Badger Bus
Bus from Minneapolis to Madison
- Ave. Duration
- 4h 45m
- Frequency
- Twice a week
- Estimated price
- $60–80
- Website
- Badger Bus
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Minneapolis to Louisville is 705 miles. It takes approximately 11h 44m to drive from Minneapolis to Louisville.
Book your Minneapolis to Louisville bus tickets online with Omio.
There are 628+ hotels available in Louisville.












