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How to get fromMinneapolis to Senecaby plane, car, bus, taxi, or train (Amtrak)

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There are 9 ways to get from Minneapolis to Seneca by plane, car, bus, taxi, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Asheville Regional Airport, drive

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Asheville Regional Airport (AVL)plane plane MSP - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    5h 24m
    $114–571

  2. Bus, taxi

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Bloomingtonbus bus
    4. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta to Flying J - Commercebus bus
    6. Take the taxi from Flying J - Commerce to Senecataxi taxi
    32h 18m
    $316–506

  3. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Charlottesvilletrain train
    3. Take the train from Charlottesville to Clemson Amtrak Stationtrain train
    41h 2m
    $466–1,202

  4. Drive  1,084 mi

    1. Drive from Minneapolis to Senecacar car 1,084 mi
    19h 52m
    $198–286

  5. Fly to Greenville–Spartanburg International Airport, taxi

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Greenville–Spartanburg International Airport (GSP)plane plane MSP - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 26m
    $292–1,022

  6. Fly to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MSP - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    8h 25m
    $312–605

  7. Fly to Mcghee Tyson Airport, drive

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Mcghee Tyson Airport (TYS)plane plane MSP - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Senecacar car
    7h 35m
    $249–1,242

  8. Bus, drive

    1. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Toledobus bus
    3. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from WNC Ag Center Park-n-Ride to Senecacar car
    34h 39m
    $251–393

  9. Train via Cary (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    43h 3m
    $506–1,292

Minneapolis–Saint Paul International Airport (MSP) to Asheville Regional Airport (AVL) flights

Calendar69Weekly Planes
Duration4h 34mAverage Duration
Ticket$103Cheapest Price
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Comparing Your Travel Options

Map of how to get from Minneapolis to Seneca.ExpandLaunch map view
  • Distance: 939.1 mi
  • Duration: 5h 24m

What companies run services between Minneapolis, MN, USA and Seneca, SC, USA?

You can take a bus from 6th St S & 5th Ave S to Seneca via Union Depot Station & Terminal, St. Paul-Minneapolis, Chicago Union Station, Charlottesville, and Clemson Amtrak Station in around 41h 2m.

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