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How to get fromMinneapolis to Sikestonby plane, car, bus (Greyhound, Flixbus), train, bus, or taxi

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There are 10 ways to get from Minneapolis to Sikeston by plane, car, bus (Greyhound, Flixbus), train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, drive

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Barkley Regional Airport (PAH)plane plane MSP - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    6h 30m
    $97–487

  2. Bus

    1. Take the bus from Minneapolis Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150 / ...
    2. Take the bus from Water & Chicago - Circle K to Flying J - Matthewsbus bus Milwaukee
    16h 38m
    $211–273

  3. Train, drive (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    19h 31m
    $224–511

  4. Drive 660.3 mi

    1. Drive from Minneapolis to Sikestoncar car 660.3 mi
    11h 49m
    $121–175

  5. Fly to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 7m
    $490–1,105

  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Williamson County Regional Airport (MWA)plane plane MSP - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    8h 4m
    $437–993

  7. Fly to Nashville, bus, drive

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Nashville (BNA)plane plane MSP - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    8h 40m
    $433–1,151

  8. Fly to Memphis, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Memphis (MEM)plane plane MSP - MEM
    2. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    8h 45m
    $228–968

  9. Train, bus

    1. Take the train from St. Paul-Minneapolis to Milwaukeetrain train Borealis / ...
    2. Take the bus from Water & Chicago - Circle K to Flying J - Matthewsbus bus Milwaukee
    17h 41m
    $216–362

  10. Bus via Minneapolis

    1. Take the bus from Minneapolis to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Water & Chicago - Circle K to Flying J - Matthewsbus bus Milwaukee
    18h 22m
    $216–280

Minneapolis–Saint Paul International Airport (MSP) to Barkley Regional Airport (PAH) flights

Calendar16Weekly Planes
Duration6h 2mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis to Sikeston.ExpandLaunch map view
  • Distance: 650.1 mi
  • Duration: 6h 30m

What companies run services between Minneapolis, MN, USA and Sikeston, MO, USA?

You can take a bus from Minneapolis Bus Station to Sikeston via Milwaukee Intermodal Station, Water & Chicago - Circle K, and Flying J - Matthews in around 16h 38m.

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