There are 7 ways to get from Minneapolis to Uptown by plane, subway, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago O'Hare International Airport, subway
best- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane MSP - ORD
- Take the subway from Lake to Wilson-North Innersubway
4h 5m$226–812Drive 403.9 mi
cheapest- Drive from Minneapolis to Uptowncar 403.9 mi
6h 39m$69–100Bus
- Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus Greyhound US0150
9h 43m$73–119Train (Amtrak)
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain Borealis / ...
10h 16m$225–355Fly to Chicago Midway International Airport, subway
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane MSP - MDW
- Take the subway from Roosevelt to Wilson-North Innersubway
3h 57m$76–472Fly to South Bend, train
- Fly from Minneapolis–Saint Paul International Airport (MSP) to South Bend (SBN)plane MSP - SBN
- Take the train from South Bend Airport to Van Buren St.train
6h 8m$88–454Bus via Madison
- Take the bus from Minneapolis to Madisonbus Jefferson Lines 965
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus Van Galder
11h 57m$89–161
Minneapolis to Uptown by bus and foot
Comparing Your Travel Options
The cheapest way to get from Minneapolis to Uptown is to drive which costs $65 - $100 and takes 6h 39m.
The fastest way to get from Minneapolis to Uptown is to fly and subway which takes 3h 57m and costs $75 - $480.
No, there is no direct bus from Minneapolis station to Uptown. However, there are services departing from Minneapolis Bus Station and arriving at Sheridan & Wilson via Union Station Transit Center. The journey, including transfers, takes approximately 9h 43m.
No, there is no direct train from Minneapolis station to Uptown station. However, there are services departing from Government Plaza Station and arriving at Chicago Union Station via St. Paul-Minneapolis. The journey, including transfers, takes approximately 10h 16m.
The distance between Minneapolis and Uptown is 367 miles. The road distance is 406.2 miles.
The best way to get from Minneapolis to Uptown without a car is to bus which takes 9h 43m and costs $70 - $120.
It takes approximately 4h 5m to get from Minneapolis to Uptown, including transfers.
Minneapolis to Uptown bus services, operated by Greyhound USA, depart from Minneapolis Bus Station.
Minneapolis to Uptown train services, operated by Amtrak, depart from St. Paul-Minneapolis station.
The best way to get from Minneapolis to Uptown is to bus which takes 9h 43m and costs $70 - $120. Alternatively, you can train, which costs $220 - $360 and takes 10h 16m.
What companies run services between Minneapolis, MN, USA and Uptown, IL, USA?
Greyhound USA operates a bus from Minneapolis Bus Station to Chicago Bus Station 3 times a day. Tickets cost $75–120 and the journey takes 8h 35m. Flixbus USA also services this route once daily. Alternatively, Amtrak operates a train from St. Paul-Minneapolis to Chicago Union Station 3 times a day. Tickets cost $220–350 and the journey takes 7h 32m.
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $50–320
Flights from Minneapolis–Saint Paul International Airport to South Bend via Chicago O'Hare International Airport
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $70–430
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $50–320
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $70–460
Flights from Minneapolis–Saint Paul International Airport to South Bend
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $70–430
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $70–460
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- aa.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $50–320
Flights from Minneapolis–Saint Paul International Airport to South Bend via Chicago O'Hare International Airport
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $70–430
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $50–320
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Lake to Wilson-North Inner
- Ave. Duration
- 22 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Subway from Roosevelt to Wilson-North Inner
- Ave. Duration
- 27 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from South Bend Airport to Van Buren St.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $14–17
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $14–17
Train from South Bend Airport to Van Buren St.
- Ave. Duration
- 2h 1m
- Frequency
- Every 4 hours
- Estimated price
- $4–16
- Schedules at
- Northern Indiana Commuter Transportation District
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Minneapolis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Minneapolis to Madison
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
- Phone
- +1 414-266-4409
- [email protected]
- Website
- Badger Bus
Bus from Minneapolis to Madison
- Ave. Duration
- 4h 45m
- Frequency
- Twice a week
- Estimated price
- $60–80
- Website
- Badger Bus
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Want to know more about travelling around United States
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Booking & Getting There
Minneapolis to Uptown bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Minneapolis to Uptown train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Minneapolis to Uptown is 406 miles. It takes approximately 6h 39m to drive from Minneapolis to Uptown.
There are 1308+ hotels available in Uptown.
















