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How to get fromMinnesota to Louisvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Amtrak)

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There are 8 ways to get from Minnesota to Louisville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Minneapolis–Saint Paul International Airport to Louisville International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    4h 30m
    $143–805

  2. Bus

    cheapest
    1. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus Greyhound US0150
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    15h 35m
    $104–181

  3. Train, bus

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    17h 38m
    $169–408

  4. Drive  701.2 mi

    1. Drive from Minneapolis to Louisvillecar car 701.2 mi
    11h 44m
    $128–185

  5. Fly Rochester to Louisville International Airport

    1. Fly from Rochester (RST) to Louisville International Airport (SDF)plane plane RST - SDF
    7h 36m
    $112–690

  6. Fly Duluth International Airport to Louisville International Airport

    1. Fly from Duluth International Airport (DLH) to Louisville International Airport (SDF)plane plane DLH - SDF
    6h 52m
    $122–704

  7. Fly Minneapolis–Saint Paul International Airport to Covington, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Covington (CVG)plane plane MSP - CVG
    2. Take the bus from Cincinnati to Louisvillebus bus
    6h 53m
    $463–1,149

  8. Bus via Madison

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus
    4. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus
    20h 40m
    $141–257

Minnesota to Louisville by bus

Calendar28Weekly Buses
Duration15h 35mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Minnesota to Louisville.ExpandLaunch map view
  • Distance: 615.5 mi
  • Duration: 4h 30m

What companies run services between Minnesota, USA and Louisville, KY, USA?

Delta, Southwest Airlines, and United Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Minneapolis Bus Station to Louisville Bus Station via Chicago Bus Station in around 15h 35m.

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