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How to get fromMinnesota to South Carolinaby plane, taxi, train (Amtrak), car, or bus

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There are 6 ways to get from Minnesota to South Carolina by plane, taxi, train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charlotte Douglas International Airport, taxi

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Charlotte Douglas International Airport (CLT)plane plane MSP - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 23m
    $242–952

  2. Fly to Myrtle Beach, bus

    cheapest
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Myrtle Beach (MYR)plane plane MSP - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 44m
    $125–584

  3. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    38h 54m
    $942–1,502

  4. Drive  1,279.8 mi

    1. Drive from Minneapolis to Charlestoncar car 1,279.8 mi
    22h 39m
    $234–338

  5. Fly to Greenville–Spartanburg International Airport

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Greenville–Spartanburg International Airport (GSP)plane plane MSP - GSP
    5h 47m
    $197–897

  6. Fly to Charleston International Airport

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Charleston International Airport (CHS)plane plane MSP - CHS
    5h 8m
    $144–704

Minneapolis–Saint Paul International Airport (MSP) to Charlotte Douglas International Airport (CLT) flights

Calendar72Weekly Planes
Duration2h 54mAverage Duration
Ticket$167Cheapest Price
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Comparing Your Travel Options

Map of how to get from Minnesota to South Carolina.ExpandLaunch map view
  • Distance: 964 mi
  • Duration: 4h 23m

What companies run services between Minnesota, USA and South Carolina, USA?

You can take a vehicle from Government Plaza Station to Charleston via Union Depot Station, St. Paul-Minneapolis, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 38h 54m. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Greenville–Spartanburg International Airport (GSP) hourly.

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