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How to get fromMission Bay to Downtown San Diegoby train, plane, bus, train (Amtrak), car, tram, subway, shuttle, or bus (Greyhound)

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There are 8 ways to get from Mission Bay to Downtown San Diego by train, plane, bus, train (Amtrak), car, tram, subway, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Caltrain to San Francisco International Airport, fly

    best
    1. Take the train from San Francisco Caltrain Southbound to Millbrae Caltrain Southboundtrain train
    2. Fly from San Francisco International Airport (SFO) to San Diego International Airport (SAN)plane plane SFO - SAN
    3h 57m
    $75–252

  2. Tram, BART to Oakland International Airport, fly

    cheapest
    1. Take the tram from Third Street & Mission Rock St to Union Square/Market St Station Northboundtram tram
    2. Take the subway from Powell Street to Coliseumsubway subway
    3. Fly from Oakland International Airport (OAK) to San Diego International Airport (SAN)plane plane OAK - SAN
    4h 16m
    $69–285

  3. Caltrain, bus

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train Local Weekday / ...
    2. Take the bus from San Jose - King Rd to San Ysidrobus bus San Jose
    13h 48m
    $104–149

  4. Caltrain, train

    1. Take the train from San Francisco Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from Los Angeles to San Diegotrain train
    17h 12m
    $177–382

  5. Drive 500.2 mi

    1. Drive from Mission Bay to Downtown San Diegocar car 500.2 mi
    8h 23m
    $92–132

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from San Francisco Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to San Diego International Airport (SAN)plane plane SJC - SAN
    4h 50m
    $84–499

  7. Shuttle to Sonoma County Airport, fly

    1. Take a shuttle bus from San Francisco Pier 27 to Santa Rosa Airportshuttle bus
    2. Fly from Sonoma County Airport (STS) to San Diego International Airport (SAN)plane plane STS - SAN
    6h 25m
    $171–314

  8. Bus (Greyhound)

    1. Take the bus from San Francisco Bus Station to San Diego Greyhound Bus Stopbus bus Greyhound US0831
    15h 10m
    $77–152

Mission Bay to Downtown San Diego by train, bus, tram, and foot

Calendar14Weekly Services
Duration13h 48mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Mission Bay to Downtown San Diego.ExpandLaunch map view
  • Distance: 468.6 mi
  • Duration: 3h 57m

What companies run services between Mission Bay, CA, USA and Downtown San Diego, CA, USA?

You can take a train from San Francisco Caltrain Southbound to Downtown San Diego via San Jose Diridon Caltrain Southbound, San Jose, Los Angeles, San Diego, Santa Fe Depot, and 11th Av & Broadway in around 17h 12m. Alternatively, Greyhound USA operates a bus from San Francisco Bus Station to San Diego Greyhound Bus Stop once daily. Tickets cost $75–150 and the journey takes 13h 15m.

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