There are 6 ways to get from Mission District to Palo Alto by train, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Caltrain
best- Take the train from San Francisco Caltrain Southbound to California Avenue Caltrain Southboundtrain Local Weekday / ...
52 min$7–10Bus
cheapest- Take the bus from Potrero Ave & 21st St to University Ave & Woodland Avebus 397
2h 10m$3–5Drive 31.4 mi
- Drive from Mission District to Palo Altocar 31.4 mi
37 min$6–9Taxi
- Take the taxi from Mission District to Palo Altotaxi 31.4 mi
37 min$110–140Bus via San Bruno
- Take the bus from San Bruno BART-Bay 8 Outer Busway to Palo Alto Transit Ctr-Bay 1bus Ecr
2h 13m$5–8Line 292 bus, bus
- Take the bus from Potrero Ave & 21st St to Millbrae Transit Center-Bay C1bus 292 / ...
- Take the bus from Millbrae Transit Center-Bay C1 to Palo Alto Transit Ctr-Bay 1bus Ecr / ...
2h 30m$4–7
Mission District to Palo Alto by train
Questions & Answers
The cheapest way to get from Mission District to Palo Alto is to bus which costs $3 - $5 and takes 2h 10m.
The fastest way to get from Mission District to Palo Alto is to drive which takes 37 min and costs $5 - $9.
Yes, there is a direct bus departing from Potrero Ave & 21st St and arriving at University Ave & Woodland Ave. Services depart every four hours, and operate every day. The journey takes approximately 2h 10m.
Yes, there is a direct train departing from San Francisco Caltrain Southbound and arriving at California Avenue Caltrain Southbound. Services depart every 30 minutes, and operate every day. The journey takes approximately 52 min.
The distance between Mission District and Palo Alto is 32 miles. The road distance is 31.5 miles.
The best way to get from Mission District to Palo Alto without a car is to Caltrain which takes 52 min and costs $7 - $10.
The Caltrain from San Francisco Caltrain Southbound to California Avenue Caltrain Southbound takes 52 min including transfers and departs every 30 minutes.
Mission District to Palo Alto bus services, operated by SamTrans, depart from Potrero Ave & 21st St station.
Mission District to Palo Alto train services, operated by Caltrain, depart from San Francisco Caltrain Southbound station.
The best way to get from Mission District to Palo Alto is to Caltrain which takes 52 min and costs $7 - $10. Alternatively, you can bus, which costs $3 - $5 and takes 2h 10m.
What companies run services between Mission District, CA, USA and Palo Alto, CA, USA?
Caltrain operates a train from San Francisco Caltrain Southbound to California Avenue Caltrain Southbound every 30 minutes. Tickets cost $7–10 and the journey takes 52 min. Alternatively, SamTrans operates a bus from Potrero Ave & 21st St to University Ave & Woodland Ave every 4 hours. Tickets cost $2–5 and the journey takes 2h 10m.
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from San Francisco Caltrain Southbound to California Avenue Caltrain Southbound
- Ave. Duration
- 52 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–10
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $7–10
- Website
- samtrans.com
Bus from Potrero Ave & 21st St to University Ave & Woodland Ave
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- $2–5
- Website
- http://www.samtrans.com
- Website
- http://www.samtrans.com
Bus from San Bruno BART-Bay 8 Outer Busway to Palo Alto Transit Ctr-Bay 1
- Ave. Duration
- 1h 44m
- Frequency
- Every 15 minutes
- Estimated price
- $2–4
- Website
- http://www.samtrans.com
- Website
- http://www.samtrans.com
Bus from Potrero Ave & 21st St to Millbrae Transit Center-Bay C1
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- $1–3
- Website
- http://www.samtrans.com
- Website
- http://www.samtrans.com
Bus from Millbrae Transit Center-Bay C1 to Palo Alto Transit Ctr-Bay 1
- Ave. Duration
- 1h 23m
- Frequency
- Every 15 minutes
- Estimated price
- $2–4
- Website
- http://www.samtrans.com
- Website
- http://www.samtrans.com
- Ave. Duration
- 37 min
- Estimated price
- $110–140
Coastside TAxi
- Phone
- +1 650-333-3505
- Website
- coastsidetaxi.com
SF Green Cab
- Phone
- +1 415-626-4733
- Website
- greencabsf.com
Yellow Cab
- Phone
- +1 415.333.3333
- Website
- yellowcabsf.com
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More Questions & Answers
Mission District to Palo Alto bus services, operated by SamTrans, arrive at University Ave & Woodland Ave station.
Mission District to Palo Alto train services, operated by Caltrain, arrive at California Avenue Caltrain Southbound station.
Yes, the driving distance between Mission District to Palo Alto is 32 miles. It takes approximately 37 min to drive from Mission District to Palo Alto.
There are 500+ hotels available in Palo Alto.




