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How to get fromMission to Chicagoby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from Mission to Chicago by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcallen Miller International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Mcallen Miller International Airport (MFE) to Chicago O'Hare International Airport (ORD)plane plane MFE - ORD
    6h 20m
    $142–579

  2. Bus to Rio Grande Valley International Airport, fly to Chicago Midway International Airport

    cheapest
    1. Take the bus from Palmview to Harlingen Bus Stationbus bus
    2. Fly from Rio Grande Valley International Airport (HRL) to Chicago Midway International Airport (MDW)plane plane HRL - MDW
    9h
    $111–490

  3. Bus

    1. Take the bus from Palmview to Laredo Bus Stationbus bus Greyhound US1169s
    2. Take the bus from Laredo to Chicagobus bus Querétaro
    30h 47m
    $227–419

  4. Bus, train via Dallas

    1. Take the bus from McAllen Central Station to Dallasbus bus Brownsville
    2. Take the train from Dallas to Chicago Union Stationtrain train Texas Eagle
    33h 52m
    $415–775

  5. Drive 1,426.3 mi

    1. Drive from Mission to Chicagocar car 1,426.3 mi
    24h 12m
    $261–376

  6. Bus, train

    1. Take the bus from McAllen Central Station to San Marcosbus bus FlixBus US1164
    2. Take the train from San Marcos Amtrak to Chicago Union Stationtrain train Texas Eagle
    39h 50m
    $457–947

Mission to Chicago by bus, foot, and subway

Calendar7Weekly Services
Duration30h 47mAverage Duration
Ticket$227Cheapest Price
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Questions & Answers

Map of how to get from Mission to Chicago.ExpandLaunch map view
  • Distance: 1,264.2 mi
  • Duration: 6h 20m

What companies run services between Mission, TX, USA and Chicago, IL, USA?

United Airlines and American Airlines fly from Mcallen Miller International Airport (MFE) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a bus from Palmview to Harold Washington Library via Laredo Bus Station, Laredo, California & 35th Street, 35th/Archer Orange Line Station, and 35th/Archer in around 30h 47m.

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Need to know: Greyhound

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