There are 6 ways to get from Mission Viejo to Henderson by train, bus, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Santa Ana to San Bernardino - Downtowntrain IE-OC Line
- Take the bus from San Bernardino Downtown Transit Center to Las Vegas Stripbus FlixBus 2037
8h 13m$96–135Drive 270.2 mi
cheapest- Drive from Mission Viejo to Hendersoncar 270.2 mi
4h 28m$45–65Fly from John Wayne Airport Orange County, line 217 bus
- Fly from John Wayne Airport Orange County (SNA) to Harry Reid International Airport (LAS)plane SNA - LAS
- Take the bus from South Strip Transit Terminal to EB Lake Mead after Boulderbus
4h 58m$110–290Bus (Flixbus)
- Take the bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtownbus FlixBus 2030
9h 59m$53–78Bus via San Bernardino
- Take the bus from Katella + Harbor to San Bernardinobus 200
- Take the bus from San Bernardino to SB Las Vegas at Fashion Show Mallbus Riverside to Las Vegas
10h 59m$56–60Line 83 bus, train to Los Angeles International Airport, fly, line 217 bus
- Take the bus from Laguna Hills Trans Ctr Dock 5 to Santa Ana-Santiagobus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Harry Reid International Airport (LAS)plane LAX - LAS
- Take the bus from South Strip Transit Terminal to EB Lake Mead after Boulderbus
6h 46m$136–323
Mission Viejo to Henderson by bus (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Mission Viejo to Henderson is to drive which costs $40 - $65 and takes 4h 28m.
The fastest way to get from Mission Viejo to Henderson is to drive which takes 4h 28m and costs $40 - $65.
No, there is no direct bus from Mission Viejo to Henderson. However, there are services departing from Laguna Hills Trans Ctr Dock 5 and arriving at SB Boulder before Lake Mead via Katella-Harbor, Anaheim Regional Transportation Intermodal Center and Bonneville Transit Center Bay 14. The journey, including transfers, takes approximately 9h 59m.
The distance between Mission Viejo and Henderson is 303 miles. The road distance is 271.8 miles.
The best way to get from Mission Viejo to Henderson without a car is to train and bus which takes 8h 13m and costs $95 - $140.
It takes approximately 8h 13m to get from Mission Viejo to Henderson, including transfers.
Mission Viejo to Henderson bus services, operated by Flixbus USA, depart from Anaheim Regional Transportation Intermodal Center station.
Mission Viejo to Henderson bus services, operated by Flixbus USA, arrive at Las Vegas Downtown station.
Yes, the driving distance between Mission Viejo to Henderson is 272 miles. It takes approximately 4h 28m to drive from Mission Viejo to Henderson.
There are 1362+ hotels available in Henderson.
What companies run services between Mission Viejo, CA, USA and Henderson, NV, USA?
Flixbus USA operates a bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtown 6 times a week. Tickets cost $45–70 and the journey takes 6h 30m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $35–250
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $28–200
- Website
- jsx.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $35–250
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $28–200
- Website
- united.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $28–200
- Website
- delta.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 21m
- When
- Sunday
- Estimated price
- $35–250
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $28–200
- Website
- aa.com
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $28–200
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–190
Flights from Los Angeles International Airport to Harry Reid International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $95–190
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $100–260
- Phone
- (800) 371-LINK (5465)
- Website
- Metrolink Trains
Train from Santa Ana to San Bernardino - Downtown
- Ave. Duration
- 1h 24m
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Website
- Metrolink Trains
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Bernardino Downtown Transit Center to Las Vegas Strip
- Ave. Duration
- 4h 5m
- Frequency
- 6 times a week
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Downtown
- Ave. Duration
- 6h 30m
- Frequency
- 6 times a week
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
- Phone
- +1 702-228-7433
- Website
- RTC
Bus from South Strip Transit Terminal to EB Lake Mead after Boulder
Bus from South Strip Transit Terminal to EB Lake Mead after Boulder
- Phone
- +1 (951) 565-5002
- Website
- Riverside Transit Agency
Bus from Katella + Harbor to San Bernardino
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- $1–5
- Website
- Riverside Transit Agency
- Adults
- $1–5
- Phone
- +1 602-698-7800
- [email protected]
- Website
- Luxury Coach of America
Bus from San Bernardino to SB Las Vegas at Fashion Show Mall
- Ave. Duration
- 4h 29m
- Frequency
- 5 times a week
- Estimated price
- $45
- Schedules at
- Luxury Coach of America
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Laguna Hills Trans Ctr Dock 5 to Santa Ana-Santiago
- Ave. Duration
- 24 min
- Frequency
- Every 30 minutes
- Estimated price
- $2
- Schedules at
- octa.net
- Adult One-way
- $2
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