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How to get fromMission Viejo to Myrtle Beachby plane, bus (Greyhound), train, bus, or car

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There are 9 ways to get from Mission Viejo to Myrtle Beach by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Wayne Airport Orange County

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR)plane plane SNA - MYR
    9h 14m
    $123–506
  2. Bus via Ciudad Juárez

    1. Take the bus from Santa Ana to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    2d 10h
    $440–645
  3. Train, bus

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    3d 3h
    $1,825–2,916
  4. Drive  2,509.7 mi

    1. Drive from Mission Viejo to Myrtle Beachcar car 2,509.7 mi
    40h 49m
    $415–599
  5. Train to Los Angeles International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Los Angeles International Airport (LAX) to Myrtle Beach (MYR)plane plane LAX - MYR
    11h
    $129–439
  6. Train to San Diego International Airport, fly

    1. Take the train from San Juan Capistrano Amtrak Station to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Myrtle Beach (MYR)plane plane SAN - MYR
    11h 32m
    $138–466
  7. Train to Burbank Bob Hope Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Fly from Burbank Bob Hope Airport (BUR) to Myrtle Beach (MYR)plane plane BUR - MYR
    12h 2m
    $138–506
  8. Train, train to Ontario International Airport, fly

    1. Take the train from Santa Ana to Los Angelestrain train
    2. Take the train from Los Angeles to Ontario Amtraktrain train
    3. Fly from Ontario International Airport (ONT) to Myrtle Beach (MYR)plane plane ONT - MYR
    12h 4m
    $174–633
  9. Bus (Greyhound)

    1. Take the bus from Santa Ana to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    2d 13h
    $476–725

Mission Viejo to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration3d 3hAverage Duration
Ticket$1,825Cheapest Price
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Comparing Your Travel Options

What companies run services between Mission Viejo, CA, USA and Myrtle Beach, SC, USA?

Southwest Airlines, Delta, and three other airlines fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR) 4 times a day. Alternatively, you can take a bus from Laguna Hills Trans Ctr Dock 5 to Myrtle Beach Bus Station via Santa Ana-Santiago, Santa Ana, El Paso, El Paso Bus Station, Houston Bus Station, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 2d 10h.

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Related travel guides

Need to know: Greyhound

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