There are 9 ways to get from Mission Viejo to Myrtle Beach by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR)plane SNA - MYR
9h 14m$123–506Bus via Ciudad Juárez
- Take the bus from Santa Ana to El Pasobus Cbx
- Take the bus from El Paso Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Atlantabus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
2d 10h$440–645Train, bus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
3d 3h$1,825–2,916Drive 2,509.7 mi
- Drive from Mission Viejo to Myrtle Beachcar 2,509.7 mi
40h 49m$415–599Train to Los Angeles International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Myrtle Beach (MYR)plane LAX - MYR
11h$129–439Train to San Diego International Airport, fly
- Take the train from San Juan Capistrano Amtrak Station to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to Myrtle Beach (MYR)plane SAN - MYR
11h 32m$138–466Train to Burbank Bob Hope Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Burbank Bob Hope Airport (BUR) to Myrtle Beach (MYR)plane BUR - MYR
12h 2m$138–506Train, train to Ontario International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Take the train from Los Angeles to Ontario Amtraktrain
- Fly from Ontario International Airport (ONT) to Myrtle Beach (MYR)plane ONT - MYR
12h 4m$174–633Bus (Greyhound)
- Take the bus from Santa Ana to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
2d 13h$476–725
Mission Viejo to Myrtle Beach by bus and train
Comparing Your Travel Options
The cheapest way to get from Mission Viejo to Myrtle Beach is to train and fly which costs $120 - $440 and takes 11h.
The fastest way to get from Mission Viejo to Myrtle Beach is to fly which takes 9h 14m and costs $120 - $550.
No, there is no direct bus from Mission Viejo to Myrtle Beach station. However, there are services departing from Laguna Hills Trans Ctr Dock 5 and arriving at Myrtle Beach Bus Station via Santa Ana, El Paso Bus Station, Houston - Harrisburg Blvd and Atlanta Bus Station. The journey, including transfers, takes approximately 2 days 10h.
The distance between Mission Viejo and Myrtle Beach is 2258 miles. The road distance is 2524.3 miles.
The best way to get from Mission Viejo to Myrtle Beach without a car is to bus via Ciudad Juárez which takes 2 days 10h and costs $440 - $650.
It takes approximately 9h 14m to get from Mission Viejo to Myrtle Beach, including transfers.
Mission Viejo to Myrtle Beach bus services, operated by CBX Cross Border Express, depart from Santa Ana station.
The best way to get from Mission Viejo to Myrtle Beach is to fly which takes 9h 14m and costs $120 - $550. Alternatively, you can bus via Ciudad Juárez, which costs $440 - $650 and takes 2 days 10h.
Mission Viejo to Myrtle Beach bus services, operated by CBX Cross Border Express, arrive at El Paso station.
Myrtle Beach is 3h ahead of Mission Viejo. It is currently 3:03 PM in Mission Viejo and 6:03 PM in Myrtle Beach.
What companies run services between Mission Viejo, CA, USA and Myrtle Beach, SC, USA?
Southwest Airlines, Delta, and three other airlines fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR) 4 times a day. Alternatively, you can take a bus from Laguna Hills Trans Ctr Dock 5 to Myrtle Beach Bus Station via Santa Ana-Santiago, Santa Ana, El Paso, El Paso Bus Station, Houston Bus Station, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 2d 10h.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Denver
- Ave. Duration
- 7h 39m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–550
Flights from Los Angeles International Airport to Myrtle Beach via Dallas
- Ave. Duration
- 7h 40m
- When
- Saturday
- Estimated price
- $90–380
Flights from Los Angeles International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 9h 22m
- When
- Saturday to Sunday
- Estimated price
- $90–380
Flights from Los Angeles International Airport to Myrtle Beach via St. Louis
- Ave. Duration
- 13h 20m
- When
- Friday
- Estimated price
- $90–380
Flights from San Diego International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 9h 35m
- When
- Every day
- Estimated price
- $90–390
Flights from San Diego International Airport to Myrtle Beach via Dallas
- Ave. Duration
- 14h 30m
- When
- Friday
- Estimated price
- $90–390
Flights from Burbank Bob Hope Airport to Myrtle Beach via Nashville
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $100–450
Flights from Burbank Bob Hope Airport to Myrtle Beach via Denver
- Ave. Duration
- 9h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–460
Flights from Ontario International Airport to Myrtle Beach via Chicago Midway
- Ave. Duration
- 7h 45m
- When
- Saturday
- Estimated price
- $130–550
Flights from Ontario International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 8h 20m
- When
- Saturday
- Estimated price
- $120–550
Flights from Ontario International Airport to Myrtle Beach via Denver
- Ave. Duration
- 9h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–550
- Website
- aa.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 7h 24m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–500
Flights from John Wayne Airport Orange County to Myrtle Beach via Charlotte
- Ave. Duration
- 9h 40m
- When
- Every day
- Estimated price
- $110–500
Flights from Los Angeles International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 7h 45m
- When
- Every day
- Estimated price
- $90–380
Flights from San Diego International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 7h 36m
- When
- Every day
- Estimated price
- $90–390
Flights from Burbank Bob Hope Airport to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 9h 50m
- When
- Every day
- Estimated price
- $100–450
Flights from Ontario International Airport to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $120–550
Flights from Ontario International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 7h 56m
- When
- Monday, Tuesday, and Sunday
- Estimated price
- $120–550
- Website
- delta.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Atlanta
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $110–490
Flights from Los Angeles International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $90–380
Flights from San Diego International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $90–390
Flights from Ontario International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $120–550
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Columbus
- Ave. Duration
- 7h 47m
- When
- Monday and Friday
- Estimated price
- $160–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $490–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from San Juan Capistrano Amtrak Station to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- $35–60
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Los Angeles to Ontario Amtrak
- Ave. Duration
- 54 min
- Frequency
- 6 times a week
- Estimated price
- $20–35
- Website
- Amtrak
- [email protected]
- Website
- Cross Border Xpress
Bus from Santa Ana to El Paso
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Website
- Cross Border Xpress
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from El Paso Bus Station to Houston Bus Station
- Ave. Duration
- 14h 45m
- Frequency
- Once daily
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Los Angeles Union Station to Dallas Bus Station
- Ave. Duration
- 29h 5m
- Frequency
- Twice daily
- Estimated price
- $260–390
- Website
- Greyhound
Bus from Dallas Bus Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- 3 times a day
- Estimated price
- $140–220
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Atlanta
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $130–170
- Schedules at
- Omnibus Express
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Santa Ana to Los Angeles Union Station
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Schedules at
- Greyhound Mexico
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Booking & Getting There
Yes, the driving distance between Mission Viejo to Myrtle Beach is 2524 miles. It takes approximately 40h 49m to drive from Mission Viejo to Myrtle Beach.
There are 5660+ hotels available in Myrtle Beach.





















