There are 4 ways to get from Mission Viejo to Myrtle Beach by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR)plane SNA - MYR
7h 32m$185–666Bus (Greyhound)
- Take the bus from Santa Ana Bus Stop to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
2d 13h$483–742Train, bus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
3d 3h$1,826–2,916Drive 2,509.7 mi
- Drive from Mission Viejo to Myrtle Beachcar 2,509.7 mi
40h 49m$429–620
Mission Viejo to Myrtle Beach by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Mission Viejo to Myrtle Beach is to fly which costs $180 - $700 and takes 7h 32m.
The fastest way to get from Mission Viejo to Myrtle Beach is to fly which takes 7h 32m and costs $180 - $700.
No, there is no direct bus from Mission Viejo to Myrtle Beach station. However, there are services departing from Laguna Hills Trans Ctr Dock 5 and arriving at Myrtle Beach Bus Station via Santa Ana Bus Stop, Los Angeles Union Station, Dallas Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 2 days 13h.
The distance between Mission Viejo and Myrtle Beach is 2254 miles. The road distance is 2524.3 miles.
The best way to get from Mission Viejo to Myrtle Beach without a car is to bus which takes 2 days 13h and costs $480 - $750.
It takes approximately 7h 32m to get from Mission Viejo to Myrtle Beach, including transfers.
Mission Viejo to Myrtle Beach bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
The best way to get from Mission Viejo to Myrtle Beach is to fly which takes 7h 32m and costs $180 - $700. Alternatively, you can bus, which costs $480 - $750 and takes 2 days 13h.
Mission Viejo to Myrtle Beach bus services, operated by Greyhound USA, arrive at Los Angeles Union Station.
Myrtle Beach is 3h ahead of Mission Viejo. It is currently 3:54 AM in Mission Viejo and 6:54 AM in Myrtle Beach.
What companies run services between Mission Viejo, CA, USA and Myrtle Beach, SC, USA?
Delta, American Airlines, and three other airlines fly from John Wayne Airport Orange County (SNA) to Myrtle Beach (MYR) 4 times a day. Alternatively, you can take a bus from Laguna Hills Trans Ctr Dock 5 to Myrtle Beach Bus Station via Santa Ana-Santiago, Santa Ana Bus Stop, Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 13h.
- Website
- delta.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Atlanta
- Ave. Duration
- 7h 45m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $130–600
- Website
- aa.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 7h 24m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–600
Flights from John Wayne Airport Orange County to Myrtle Beach via Charlotte
- Ave. Duration
- 9h 40m
- When
- Every day
- Estimated price
- $130–600
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Denver
- Ave. Duration
- 9h 39m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–600
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Myrtle Beach via Columbus
- Ave. Duration
- 7h 47m
- When
- Monday and Friday
- Estimated price
- $170–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $490–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Santa Ana Bus Stop to Los Angeles Union Station
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $6–10
- Website
- Greyhound
Bus from Los Angeles Union Station to Dallas Bus Station
- Ave. Duration
- 29h 5m
- Frequency
- 4 times a day
- Estimated price
- $260–400
- Website
- Greyhound
Bus from Dallas Bus Station to Atlanta Bus Station
- Ave. Duration
- 18h 5m
- Frequency
- Every 4 hours
- Estimated price
- $150–230
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Mission Viejo to Myrtle Beach is 2524 miles. It takes approximately 40h 49m to drive from Mission Viejo to Myrtle Beach.
There are 5586+ hotels available in Myrtle Beach.








