There are 6 ways to get from Mission Viejo to Palo Alto by plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Norman Y. Mineta San José International Airport
best- Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane SNA - SJC
2h 30m$241–861Bus via Los Angeles
cheapest- Take the bus from Laguna Hills Trans Ctr Dock 5 to Fullerton Park And Ride Dock 5bus 83
- Take the bus from Fullerton Park & Ride Dock 14 to 6th / Los Angelesbus 460
- Take the bus from Los Angeles Downtown to San Josebus
15h 44m$50–79Bus (Greyhound)
- Take the bus from Santa Ana Bus Stop to San Jose Diridon Stationbus Greyhound US0831
10h 15m$62–119Train (Amtrak)
- Take the train from Santa Ana to Los Angelestrain Pacific Surfliner
- Take the train from Los Angeles to San Josetrain Coast Starlight
13h 48m$148–312Drive 402.8 mi
- Drive from Mission Viejo to Palo Altocar 402.8 mi
6h 48m$74–107Fly to San Francisco International Airport, Caltrain
- Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane SNA - SFO
- Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain
2h 45m$237–770
Mission Viejo to Palo Alto by bus and train (Greyhound)
Questions & Answers
The cheapest way to get from Mission Viejo to Palo Alto is to bus via Los Angeles which costs $50 - $80 and takes 15h 44m.
The fastest way to get from Mission Viejo to Palo Alto is to fly which takes 2h 30m and costs $240 - $900.
No, there is no direct bus from Mission Viejo to Palo Alto station. However, there are services departing from Laguna Hills Trans Ctr Dock 5 and arriving at San Jose Diridon Station via Santa Ana Bus Stop. The journey, including transfers, takes approximately 10h 15m.
No, there is no direct train from Mission Viejo to Palo Alto. However, there are services departing from Santa Ana and arriving at California Avenue Caltrain Northbound via Los Angeles and San Jose Diridon Caltrain Northbound. The journey, including transfers, takes approximately 13h 48m.
The distance between Mission Viejo and Palo Alto is 375 miles. The road distance is 405.2 miles.
The best way to get from Mission Viejo to Palo Alto without a car is to bus which takes 10h 15m and costs $60 - $120.
It takes approximately 2h 30m to get from Mission Viejo to Palo Alto, including transfers.
Mission Viejo to Palo Alto bus services, operated by Greyhound USA, depart from Santa Ana Bus Stop station.
Mission Viejo to Palo Alto train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Mission Viejo to Palo Alto is to fly which takes 2h 30m and costs $240 - $900. Alternatively, you can bus, which costs $60 - $120 and takes 10h 15m, you could also train, which costs $140 - $320 and takes 13h 48m.
What companies run services between Mission Viejo, CA, USA and Palo Alto, CA, USA?
Southwest Airlines flies from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC) every 4 hours. Alternatively, Greyhound USA operates a bus from Santa Ana Bus Stop to San Jose Diridon Station once daily. Tickets cost $55–110 and the journey takes 8h 10m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $50–340
Flights from John Wayne Airport Orange County to San Francisco International Airport via Las Vegas
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–270
- Website
- alaskaair.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $100–320
- Website
- united.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–230
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–290
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from Millbrae Caltrain Southbound to California Avenue Caltrain Southbound
- Ave. Duration
- 31 min
- Frequency
- Every 30 minutes
- Estimated price
- $5–7
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $5–7
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Santa Ana Bus Stop to San Jose Diridon Station
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Laguna Hills Trans Ctr Dock 5 to Fullerton Park And Ride Dock 5
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1-323-466-3876
- [email protected]
- Website
- metro.net
Bus from Fullerton Park & Ride Dock 14 to 6th / Los Angeles
- Ave. Duration
- 1h 42m
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Website
- https://www.metro.net
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Los Angeles Downtown to San Jose
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $45–70
- Titanium
- $50–65
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More Questions & Answers
Mission Viejo to Palo Alto bus services, operated by Greyhound USA, arrive at San Jose Diridon Station.
Mission Viejo to Palo Alto train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Mission Viejo to Palo Alto is 405 miles. It takes approximately 6h 48m to drive from Mission Viejo to Palo Alto.
There are 498+ hotels available in Palo Alto.


















