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How to get fromMission Viejo to San Franciscoby plane, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 7 ways to get from Mission Viejo to San Francisco by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2h 15m
    $233–764

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Santa Ana Bus Stop to San Francisco Bus Stationbus bus Greyhound US0831
    11h 9m
    $67–132

  3. Train (Amtrak)

    1. Take the train from Santa Ana to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Oaklandtrain train Coast Starlight
    15h 2m
    $156–339

  4. Drive 428.5 mi

    1. Drive from Mission Viejo to San Franciscocar car 428.5 mi
    7h 8m
    $79–113

  5. Fly to Oakland International Airport

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2h 18m
    $289–810

  6. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    3h 24m
    $246–867

  7. Train, bus

    1. Take the train from Santa Ana to L.A. Union Stationtrain train OC Line
    2. Take the bus from Los Angeles Union Station to San Franciscobus bus FlixBus 2005
    12h 13m
    $75–134

Mission Viejo to San Francisco by bus (Greyhound)

Calendar14Weekly Buses
Duration11h 9mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Mission Viejo to San Francisco.ExpandLaunch map view
  • Distance: 399.3 mi
  • Duration: 2h 15m

What companies run services between Mission Viejo, CA, USA and San Francisco, CA, USA?

Frontier Airlines, Alaska Airlines, Inc., and two other airlines fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO) hourly. Alternatively, Greyhound USA operates a bus from Santa Ana Bus Stop to San Francisco Bus Station twice daily. Tickets cost $65–130 and the journey takes 9h 45m.

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Need to know: Greyhound

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