There are 5 ways to get from Mission Viejo to San Luis Obispo by bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Santa Ana to Los Angeles Union Stationbus Tijuana
- Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus FlixBus 2005
7h 24m$41–66Train (Amtrak)
- Take the train from Santa Ana to San Luis Obispotrain Pacific Surfliner
7h 57m$82–172Drive 232.7 mi
- Drive from Mission Viejo to San Luis Obispocar 232.7 mi
4h 17m$43–62Line 83 bus, train to Los Angeles International Airport, fly
- Take the bus from Laguna Hills Trans Ctr Dock 5 to Santa Ana-Santiagobus
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to San Luis Obispo County Regional Airport (SBP)plane LAX - SBP
6h 18m$260–640Train to San Diego International Airport, fly
- Take the train from San Juan Capistrano Amtrak Station to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane SAN - SBP
6h 47m$194–399
Mission Viejo to San Luis Obispo by bus
Questions & Answers
The cheapest way to get from Mission Viejo to San Luis Obispo is to bus which costs $40 - $70 and takes 7h 24m.
The fastest way to get from Mission Viejo to San Luis Obispo is to drive which takes 4h 17m and costs $40 - $65.
No, there is no direct bus from Mission Viejo to San Luis Obispo. However, there are services departing from Laguna Hills Trans Ctr Dock 5 and arriving at San Luis Obispo Railroad Museum via Santa Ana and Los Angeles Union Station. The journey, including transfers, takes approximately 7h 24m.
No, there is no direct train from Mission Viejo to San Luis Obispo. However, there are services departing from Santa Ana and arriving at San Luis Obispo via . The journey, including transfers, takes approximately 7h 57m.
The distance between Mission Viejo and San Luis Obispo is 241 miles. The road distance is 234.1 miles.
The best way to get from Mission Viejo to San Luis Obispo without a car is to bus which takes 7h 24m and costs $40 - $70.
It takes approximately 7h 24m to get from Mission Viejo to San Luis Obispo, including transfers.
Mission Viejo to San Luis Obispo bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Mission Viejo to San Luis Obispo train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Mission Viejo to San Luis Obispo is to bus which takes 7h 24m and costs $40 - $70. Alternatively, you can train, which costs $80 - $180 and takes 7h 57m.
What companies run services between Mission Viejo, CA, USA and San Luis Obispo, CA, USA?
You can take a bus from Laguna Hills Trans Ctr Dock 5 to San Luis Obispo Railroad Museum via Santa Ana-Santiago, Santa Ana, and Los Angeles Union Station in around 7h 24m. Alternatively, Amtrak operates a train from Santa Ana to San Luis Obispo twice daily. Tickets cost $80–170 and the journey takes 6h 33m.
- Website
- united.com
Flights from Los Angeles International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $26–190
Flights from San Diego International Airport to San Luis Obispo County Regional Airport via Los Angeles International Airport
- Ave. Duration
- 2h 58m
- When
- Wednesday
- Estimated price
- $30–200
- Website
- alaskaair.com
Flights from San Diego International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $170–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Santa Ana to San Luis Obispo
- Ave. Duration
- 6h 33m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- Amtrak
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $10–23
- Website
- Amtrak
Train from San Juan Capistrano Amtrak Station to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
.jpg "Pacific Surfliner interior")
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Santa Ana to Los Angeles Union Station
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $10–14
- Schedules at
- Greyhound Mexico
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Union Station to San Luis Obispo Railroad Museum
- Ave. Duration
- 4h
- Frequency
- 4 times a week
- Estimated price
- $29–50
- Schedules at
- Flixbus USA
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Laguna Hills Trans Ctr Dock 5 to Santa Ana-Santiago
- Ave. Duration
- 24 min
- Frequency
- Every 30 minutes
- Estimated price
- $2
- Schedules at
- octa.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Mission Viejo to San Luis Obispo bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Mission Viejo to San Luis Obispo train services, operated by Amtrak, arrive at San Luis Obispo station.
Yes, the driving distance between Mission Viejo to San Luis Obispo is 234 miles. It takes approximately 4h 17m to drive from Mission Viejo to San Luis Obispo.
There are 273+ hotels available in San Luis Obispo.