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How to get fromMississauga to Charlotteby plane, bus, train (Amtrak), car, shuttle, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Mississauga to Charlotte by plane, bus, train (Amtrak), car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Toronto Pearson International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane plane YYZ - CLT
    5h 10m
    $487–1,908

  2. Bus via Charleston

    cheapest
    1. Take the bus from Mississauga to Buffalobus bus
    2. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    4. Take the bus from Charleston, WV to Statesvillebus bus
    5. Take the bus from Statesville to Charlotte Bus Stationbus bus
    21h 33m
    $91–289

  3. Train

    1. Take the train from Oakville to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    27h 41m
    $305–685

  4. Drive  740 mi

    1. Drive from Mississauga to Charlottecar car 740 mi
    12h 42m
    $170–245

  5. Shuttle to Buffalo Niagara International Airport, fly

    1. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    6h 36m
    $197–728

  6. Drive to Erie International Airport, fly

    1. Drive from Mississauga to Erie-Airport-ERIcar car
    2. Fly from Erie International Airport (ERI) to Charlotte Douglas International Airport (CLT)plane plane ERI - CLT
    6h 7m
    $125–554

  7. Bus

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus FlixBus N2706
    2. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus Greyhound US0140
    22h 55m
    $127–240

Mississauga to Charlotte by bus

Calendar7Weekly Buses
Duration21h 33mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Mississauga to Charlotte.ExpandLaunch map view
  • Distance: 606.6 mi
  • Duration: 5h 10m

What companies run services between Mississauga, ON, Canada and Charlotte, NC, USA?

American Airlines, Air Canada, and United Airlines fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT) hourly. Alternatively, you can take a bus from City Centre Transit Terminal Platform O to Charlotte Bus Station via Mississauga, Buffalo, NY, Robert K Pfaff Transit Center - Akron, Charleston, WV, and Statesville in around 21h 33m.

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