There are 6 ways to get from Mississauga to Charlotte by plane, bus (Flixbus, Greyhound), train (Amtrak), car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Toronto Pearson International Airport
best- Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane YYZ - CLT
5h 12m$87–478Bus
- Take the bus from Mississauga to Detroit Bus Stationbus FlixBus N2706
- Take the bus from Detroit Bus Station to Charlotte Bus Stationbus Greyhound US0140
22h 55m$133–253Train
- Take the train from Oakville to New York Penn Stationtrain VIA Rail
- Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain Crescent / ...
27h 44m$295–675Drive 740 mi
- Drive from Mississauga to Charlottecar 740 mi
12h 42m$170–245Shuttle to Buffalo Niagara International Airport, fly
- Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airport
- Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane BUF - CLT
6h 38m$197–728Bus via Columbus
- Take the bus from Mississauga to Buffalobus
- Take the bus from Buffalo to Columbusbus
- Take the bus from Columbus to Charlottebus
23h 38m$103–244
Mississauga to Charlotte by bus
Questions & Answers
The cheapest way to get from Mississauga to Charlotte is to bus which costs $130 - $260 and takes 22h 55m.
The fastest way to get from Mississauga to Charlotte is to fly which takes 5h 12m and costs $85 - $480.
No, there is no direct bus from Mississauga to Charlotte station. However, there are services departing from Mississauga and arriving at Charlotte Bus Station via Detroit Bus Station. The journey, including transfers, takes approximately 22h 55m.
No, there is no direct train from Mississauga to Charlotte station. However, there are services departing from Oakville and arriving at Charlotte Amtrak Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 27h 44m.
The distance between Mississauga and Charlotte is 610 miles. The road distance is 744.3 miles.
The best way to get from Mississauga to Charlotte without a car is to bus which takes 22h 55m and costs $130 - $260.
It takes approximately 5h 12m to get from Mississauga to Charlotte, including transfers.
Mississauga to Charlotte bus services, operated by Flixbus USA, depart from Mississauga station.
Mississauga to Charlotte train services, operated by VIA Rail, depart from Oakville station.
The best way to get from Mississauga to Charlotte is to fly which takes 5h 12m and costs $85 - $480. Alternatively, you can bus, which costs $130 - $260 and takes 22h 55m, you could also train, which costs $290 - $700 and takes 27h 44m.
What companies run services between Mississauga, ON, Canada and Charlotte, NC, USA?
American Airlines, Air Canada, and United Airlines fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT) hourly. Alternatively, you can take a bus from Mississauga to Charlotte Bus Station via Detroit Bus Station in around 22h 55m.
- Website
- aa.com
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $80–470
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $90–500
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $100–600
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Philadelphia
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $110–650
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $100–600
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Oakville to New York Penn Station
- Ave. Duration
- 12h 31m
- Frequency
- Once daily
- Estimated price
- $140–320
- Website
- VIA Rail
- Escape
- $140–300
- Business
- $180–300
- Business Plus
- $190–310
- Economy
- $150–310
- Economy Plus
- $170–320
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Mississauga to Detroit Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 5 times a week
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Mississauga to Charlotte bus services, operated by Flixbus USA, arrive at Detroit Bus Station.
Mississauga to Charlotte train services, operated by VIA Rail, arrive at New York Penn Station.
Yes, the driving distance between Mississauga to Charlotte is 744 miles. It takes approximately 12h 42m to drive from Mississauga to Charlotte.
Book your Mississauga to Charlotte bus tickets online with Omio and FlixBus.
There are 932+ hotels available in Charlotte.