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How to get fromMississauga to Charlotteby plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Mississauga to Charlotte by plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Toronto Pearson International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane plane YYZ - CLT
    5h 9m
    $102–557

  2. Bus via Charleston

    cheapest
    1. Take the bus from Mississauga to Buffalobus bus
    2. Take the bus from Buffalo to Akronbus bus
    3. Take the bus from Akron to Charlestonbus bus
    4. Take the bus from Charleston to Charlottebus bus
    20h 38m
    $92–259

  3. Train

    1. Take the train from Toronto Union Station to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    28h 4m
    $475–886

  4. Drive  740 mi

    1. Drive from Mississauga to Charlottecar car 740 mi
    12h 40m
    $153–220

  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Mississauga to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    8h 12m
    $127–717

  6. Bus

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus FlixBus N2706
    2. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus Greyhound US0140
    22h 55m
    $156–243

Mississauga to Charlotte by bus

Calendar7Weekly Buses
Duration20h 38mAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississauga to Charlotte.ExpandLaunch map view
  • Distance: 606.5 mi
  • Duration: 5h 9m

What companies run services between Mississauga, ON, Canada and Charlotte, NC, USA?

American Airlines, Air Canada, and United Airlines fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT) every 4 hours. Alternatively, you can take a bus from City Centre Transit Terminal Platform O to Charlotte via Mississauga, Buffalo, Akron, and Charleston in around 20h 38m.

Airlines
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Want to know more about travelling around United States

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Need to know: Greyhound

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