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How to get fromMississauga to Durhamby plane, bus (Flixbus), train (Amtrak), car, shuttle, train, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Mississauga to Durham by plane, bus (Flixbus), train (Amtrak), car, shuttle, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Toronto Pearson International Airport to Raleigh-Durham International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU)plane plane YYZ - RDU
    5h 49m
    $440–1,811

  2. Bus

    cheapest
    1. Take the bus from Mississauga to Newarkbus bus Adt N809
    2. Take the bus from Newark Penn Station to Durhambus bus Greyhound US0670
    25h 38m
    $133–444

  3. Bus via Union Station Bus Terminal (Flixbus)

    1. Take the bus from Toronto to New York Midtownbus bus FlixBus N2768a / ...
    2. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    23h 19m
    $150–256

  4. Train

    1. Take the train from Oakville to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    28h 2m
    $285–655

  5. Drive  662.2 mi

    1. Drive from Mississauga to Durhamcar car 662.2 mi
    14h 6m
    $152–219

  6. Shuttle to Buffalo Niagara International Airport, fly to Raleigh-Durham International Airport

    1. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    7h 5m
    $220–551

  7. Fly Toronto Island Airport to Raleigh-Durham International Airport

    1. Fly from Toronto Island Airport (YTZ) to Raleigh-Durham International Airport (RDU)plane plane YTZ - RDU
    8h 26m
    $562–1,714

  8. Fly Toronto Pearson International Airport to Piedmont Triad International Airport, train

    1. Fly from Toronto Pearson International Airport (YYZ) to Piedmont Triad International Airport (GSO)plane plane YYZ - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    8h 39m
    $147–675

Mississauga to Durham by bus (Flixbus)

Calendar16Weekly Buses
Duration23h 19mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Mississauga to Durham.ExpandLaunch map view
  • Distance: 567.9 mi
  • Duration: 5h 49m

What companies run services between Mississauga, ON, Canada and Durham, NC, USA?

Air Canada, American Airlines, and two other airlines fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU) every 4 hours. Alternatively, you can take a bus from Rathburn Rd. W. @ Mavis Rd. to Durham via Union Station Bus Terminal, Toronto, and New York Midtown in around 23h 19m.

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