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How to get fromMississauga to Durhamby plane, bus, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mississauga to Durham by plane, bus, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Toronto Pearson International Airport to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU)plane plane YYZ - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    5h 46m
    $85–450

  2. Bus via Union Station Bus Terminal (Flixbus)

    1. Take the bus from Toronto to New York Midtownbus bus FlixBus N2768a / ...
    2. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    23h 19m
    $169–255

  3. Train

    1. Take the train from Toronto Union Station to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    28h 25m
    $445–806

  4. Drive  662.2 mi

    1. Drive from Mississauga to Durhamcar car 662.2 mi
    14h 6m
    $152–219

  5. Fly Toronto Island Airport to Raleigh-Durham International Airport

    1. Fly from Toronto Island Airport (YTZ) to Raleigh-Durham International Airport (RDU)plane plane YTZ - RDU
    8h 3m
    $91–492

  6. Bus to Buffalo Niagara International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Mississauga to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    10h 31m
    $150–300

  7. Fly Toronto Pearson International Airport to Piedmont Triad International Airport, train

    1. Fly from Toronto Pearson International Airport (YYZ) to Piedmont Triad International Airport (GSO)plane plane YYZ - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    8h 42m
    $118–429

  8. Train to Rochester, fly to Raleigh-Durham International Airport

    1. Take the train from Oakville to Rochestertrain train
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    10h 36m
    $179–925

  9. Bus

    1. Take the bus from Mississauga to Newarkbus bus Adt N809-D / ...
    2. Take the bus from Newark Penn Station to Durhambus bus Greyhound US0670
    26h 8m
    $143–444

Mississauga to Durham by bus (Flixbus)

Calendar16Weekly Buses
Duration23h 19mAverage Duration
Ticket$169Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississauga to Durham.ExpandLaunch map view
  • Distance: 567.9 mi
  • Duration: 5h 46m

What companies run services between Mississauga, ON, Canada and Durham, NC, USA?

You can take a bus from Rathburn Rd. W. @ Mavis Rd. to Durham via Union Station Bus Terminal, Toronto, and New York Midtown in around 23h 19m. Alternatively, you can take a train from Erindale GO to Durham Amtrak Station via Toronto Union Station, Penn Station, and Ny Moynihan Train Hall At Penn Station in around 28h 25m.

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