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How to get fromMississauga to Florenceby plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

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There are 5 ways to get from Mississauga to Florence by plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Florence Regional Airport (FLO)plane plane YYZ - FLO
    6h 35m
    $79–358

  2. Bus via New York

    1. Take the bus from Mississauga to New Yorkbus bus Adt N801 / ...
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    26h 1m
    $156–447

  3. Train

    1. Take the train from Oakville to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    29h 52m
    $345–746

  4. Drive 809.3 mi

    1. Drive from Mississauga to Florencecar car 809.3 mi
    16h 19m
    $186–268

  5. Bus

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    27h 30m
    $156–299

Mississauga to Florence by bus and train

Calendar7Weekly Services
Duration29h 52mAverage Duration
Ticket$345Cheapest Price
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Questions & Answers

Map of how to get from Mississauga to Florence.ExpandLaunch map view
  • Distance: 668.1 mi
  • Duration: 6h 35m

What companies run services between Mississauga, ON, Canada and Florence, SC, USA?

American Airlines and Air Canada fly from Toronto Pearson International Airport (YYZ) to Florence Regional Airport (FLO) every 4 hours. Alternatively, you can take a bus from City Centre Transit Terminal Platform O to Florence, SC via Mississauga, New York, 42 St-Times Square, Canal St, and New York, NY in around 26h 1m.

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