There are 12 ways to get from Mississauga to Frederick by plane, bus, bus (Flixbus, Greyhound), train, car, subway, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Toronto Pearson International Airport to Ronald Reagan Washington National Airport, bus
best- Fly from Toronto Pearson International Airport (YYZ) to Ronald Reagan Washington National Airport (DCA)plane YYZ - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
6h 47m$560–4,513Fly Toronto Pearson International Airport to Washington Dulles International Airport, subway, bus
cheapest- Fly from Toronto Pearson International Airport (YYZ) to Washington Dulles International Airport (IAD)plane YYZ - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
7h 18m$65–362Bus via Erie
- Take the bus from Toronto to Eriebus
- Take the bus from Erie to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus
15h 39m$93–145Train, bus
- Take the train from Oakville to New York Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus Bwi
19h 44mDrive 391.4 mi
- Drive from Mississauga to Frederickcar 391.4 mi
8h 44m$90–130Fly Toronto Island Airport to Washington Dulles International Airport, subway, bus
- Fly from Toronto Island Airport (YTZ) to Washington Dulles International Airport (IAD)plane YTZ - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
7h 43m$131–494Bus to Buffalo Niagara International Airport, fly to Baltimore-Washington International Airport, bus
- Take the bus from Mississauga to Buffalobus
- Fly from Buffalo Niagara International Airport (BUF) to Baltimore-Washington International Airport (BWI)plane BUF - BWI
- Take the bus from Baltimore to Frederickbus
8h 58m$149–574Bus to Buffalo Niagara International Airport, fly to Ronald Reagan Washington National Airport, bus
- Take the bus from Mississauga to Buffalobus
- Fly from Buffalo Niagara International Airport (BUF) to Ronald Reagan Washington National Airport (DCA)plane BUF - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
9h 39m$110–623Bus to Buffalo Niagara International Airport, fly to Washington Dulles International Airport, subway, bus
- Take the bus from Mississauga to Buffalobus
- Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane BUF - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
10h 14m$90–482Fly Toronto Pearson International Airport to Philadelphia International Airport, train, bus
- Fly from Toronto Pearson International Airport (YYZ) to Philadelphia International Airport (PHL)plane YYZ - PHL
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus
8h 40mBus
- Take the bus from Mississauga to Buffalobus
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus
16h 58m$108–334Train
- Take the train from Toronto Union Station to New York Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
20h 33m$267–538
Mississauga to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Mississauga to Frederick is to bus via Erie which costs $90 - $150 and takes 15h 39m.
The fastest way to get from Mississauga to Frederick is to fly and bus which takes 6h 47m and costs $550 - $4,600.
No, there is no direct bus from Mississauga to Frederick station. However, there are services departing from Rathburn Rd. W. @ Mavis Rd. and arriving at Frederick Bus Station via Toronto, Erie and Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 15h 39m.
No, there is no direct train from Mississauga to Frederick. However, there are services departing from Erindale GO and arriving at FREDERICK MARC wb via Toronto Union Station, Ny Moynihan Train Hall At Penn Station and Washington Union Station. The journey, including transfers, takes approximately 20h 33m.
The distance between Mississauga and Frederick is 424 miles. The road distance is 393.6 miles.
The best way to get from Mississauga to Frederick without a car is to bus via Erie which takes 15h 39m and costs $90 - $150.
It takes approximately 6h 47m to get from Mississauga to Frederick, including transfers.
Mississauga to Frederick bus services, operated by Flixbus USA, depart from Toronto station.
Mississauga to Frederick train services, operated by VIA Rail, depart from Toronto Union Station.
The best way to get from Mississauga to Frederick is to bus via Erie which takes 15h 39m and costs $90 - $150. Alternatively, you can train, which costs $260 - $550 and takes 20h 33m.
What companies run services between Mississauga, ON, Canada and Frederick, MD, USA?
You can take a bus from Rathburn Rd. W. @ Mavis Rd. to Frederick Bus Station via Union Station Bus Terminal, Toronto, Erie, and Pittsburgh Intermodal Station in around 15h 39m. Alternatively, you can take a train from Erindale GO to FREDERICK MARC wb via Toronto Union Station, Penn Station, Ny Moynihan Train Hall At Penn Station, and Washington Union Station in around 20h 33m.
- Website
- aa.com
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–470
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport via Philadelphia International Airport
- Ave. Duration
- 3h 59m
- When
- Monday to Friday
- Estimated price
- $80–500
Flights from Buffalo Niagara International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $80–550
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $55–360
Flights from Toronto Pearson International Airport to Philadelphia International Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $65–390
- Website
- united.com
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $70–470
Flights from Toronto Pearson International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $55–350
Flights from Toronto Pearson International Airport to Washington Dulles International Airport via Ottawa
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $75–420
Flights from Toronto Pearson International Airport to Washington Dulles International Airport via Raleigh/Durham
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $80–440
Flights from Toronto Island Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $55–380
Flights from Buffalo Niagara International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–410
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $55–360
Flights from Toronto Pearson International Airport to Philadelphia International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $65–390
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $55–400
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $70–470
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport via Ottawa
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $100–550
Flights from Toronto Pearson International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $55–350
Flights from Toronto Pearson International Airport to Washington Dulles International Airport via Ottawa
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $75–420
Flights from Toronto Pearson International Airport to Washington Dulles International Airport via Raleigh/Durham
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $80–440
Flights from Toronto Island Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $55–380
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $55–360
- Website
- flyporter.com
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–470
Flights from Toronto Island Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $120–430
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $55–360
- Website
- delta.com
Flights from Toronto Pearson International Airport to Ronald Reagan Washington National Airport via Detroit
- Ave. Duration
- 4h 11m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $95–550
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Oakville to New York Penn Station
- Ave. Duration
- 12h 31m
- Frequency
- Once daily
- Estimated price
- $140–320
- Website
- VIA Rail
- Escape
- $140–310
- Business
- $180–300
- Business Plus
- $190–310
- Economy
- $150–310
- Economy Plus
- $170–320
Train from Toronto Union Station to New York Penn Station
- Ave. Duration
- 12h 56m
- Frequency
- Once daily
- Estimated price
- $140–330
- Website
- VIA Rail
- Escape
- $140–320
- Business
- $180–310
- Business Plus
- $190–320
- Economy
- $160–320
- Economy Plus
- $180–330
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- $100–170
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Washington Union Station
- Ave. Duration
- 3h 35m
- Frequency
- Hourly
- Estimated price
- $120–190
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 2h 32m
- Frequency
- 5 times a day
- Estimated price
- $45–700
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $45–480
- First Class
- $180–700
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Ny Moynihan Train Hall At Penn Station to Washington Union Station
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 49 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 49 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 49 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from Washington Union Station to FREDERICK MARC wb
- Ave. Duration
- 1h 41m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Toronto to Erie
- Ave. Duration
- 4h 50m
- Frequency
- 4 times a week
- Estimated price
- $30–45
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Erie to Pittsburgh Intermodal Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Frederick Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Frederick Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from BWI Amtrak Station to Frederick Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Website
- Amtrak
Bus from BWI Amtrak Station to Frederick Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Website
- Amtrak
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Mississauga to Buffalo
- Saver
- $21–55
- Flexible
- $40–60
Bus from Mississauga to Buffalo
- Saver
- $21–55
- Flexible
- $40–60
Bus from Mississauga to Buffalo
- Saver
- $21–55
- Flexible
- $40–60
Bus from Mississauga to Buffalo
- Saver
- $20–50
- Flexible
- $40–55
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Mississauga to Frederick bus services, operated by Flixbus USA, arrive at Erie station.
Mississauga to Frederick train services, operated by VIA Rail, arrive at New York Penn Station.
Yes, the driving distance between Mississauga to Frederick is 394 miles. It takes approximately 8h 44m to drive from Mississauga to Frederick.
Book your Mississauga to Frederick bus tickets online with Omio.
There are 66+ hotels available in Frederick.



























