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How to get fromMississauga to Louisvilleby plane, train, bus, car, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Mississauga to Louisville by plane, train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Toronto Pearson International Airport to Louisville International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    7h 30m
    $95–558

  2. Bus via Akron

    cheapest
    1. Take the bus from Mississauga to Buffalobus bus
    2. Take the bus from Buffalo to Akronbus bus
    3. Take the bus from Akron to Louisvillebus bus
    16h 58m
    $80–209

  3. Train, bus

    1. Take the train from Oakville to Windsortrain train VIA Rail
    2. Take the bus from Detroit Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    14h 8m
    $111–297

  4. Drive  569.3 mi

    1. Drive from Mississauga to Louisvillecar car 569.3 mi
    9h 37m
    $131–189

  5. Fly Toronto Island Airport to Louisville International Airport

    1. Fly from Toronto Island Airport (YTZ) to Louisville International Airport (SDF)plane plane YTZ - SDF
    8h 21m
    $127–711

  6. Bus to Buffalo Niagara International Airport, fly to Louisville International Airport

    1. Take the bus from Mississauga to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    10h 44m
    $135–767

  7. Fly Toronto Pearson International Airport to Covington, bus

    1. Fly from Toronto Pearson International Airport (YYZ) to Covington (CVG)plane plane YYZ - CVG
    2. Take the bus from Cincinnati to Louisvillebus bus
    7h 51m
    $615–1,052

  8. Fly Toronto Pearson International Airport to Indianapolis, bus

    1. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    8h 16m
    $106–504

  9. Bus

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus FlixBus N2706
    2. Take the bus from Detroit Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    14h 30m
    $89–141

Mississauga to Louisville by bus, train, and car

Calendar14Weekly Services
Duration14h 8mAverage Duration
Ticket$111Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississauga to Louisville.ExpandLaunch map view
  • Distance: 512.5 mi
  • Duration: 7h 30m

What companies run services between Mississauga, ON, Canada and Louisville, KY, USA?

Delta, United Airlines, and American Airlines fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Mississauga to Louisville Bus Station via Detroit Bus Station in around 14h 30m.

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