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How to get fromMississauga to Louisvilleby plane, train, bus, car, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

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There are 8 ways to get from Mississauga to Louisville by plane, train, bus, car, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Toronto Pearson International Airport to Louisville International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    5h 11m
    $105–657

  2. Fly Toronto Pearson International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Toronto Pearson International Airport (YYZ) to Blue Grass Airport (LEX)plane plane YYZ - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 18m
    $71–353

  3. Train, bus

    1. Take the train from Oakville to Windsortrain train
    2. Take the bus from Detroit to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 57m
    $104–332

  4. Drive  569.3 mi

    1. Drive from Mississauga to Louisvillecar car 569.3 mi
    9h 37m
    $118–170

  5. Fly Toronto Island Airport to Louisville International Airport

    1. Fly from Toronto Island Airport (YTZ) to Louisville International Airport (SDF)plane plane YTZ - SDF
    9h 5m
    $137–773

  6. Bus to Buffalo Niagara International Airport, fly to Louisville International Airport

    1. Take the bus from Mississauga to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    10h 28m
    $145–817

  7. Bus

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus
    2. Take the bus from Detroit to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 20m
    $86–169

  8. Bus via Detroit

    1. Take the bus from Mississauga to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 35m
    $109–179

Mississauga to Louisville by bus, train, and car

Calendar7Weekly Services
Duration14h 57mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississauga to Louisville.ExpandLaunch map view
  • Distance: 512.5 mi
  • Duration: 5h 11m

What companies run services between Mississauga, ON, Canada and Louisville, KY, USA?

Air Canada and Delta fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from Mississauga to Louisville, KY via Detroit and Indianapolis Union Station in around 15h 20m.

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Bus operators

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