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How to get fromMississippi to Buffaloby plane, bus (Greyhound, Flixbus), train, bus, car, or train (Amtrak)

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There are 7 ways to get from Mississippi to Buffalo by plane, bus (Greyhound, Flixbus), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Memphis to Buffalo Niagara International Airport

    best
    1. Fly from Memphis (MEM) to Buffalo Niagara International Airport (BUF)plane plane MEM - BUF
    5h 6m
    $204–1,005

  2. Bus

    cheapest
    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Buffalobus bus
    26h 5m
    $179–357

  3. Train, bus

    1. Take the train from Jackson to Chicago Union Stationtrain train
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    27h 49m
    $296–632

  4. Drive 1,090.1 mi

    1. Drive from Jackson to Buffalocar car 1,090.1 mi
    19h 12m
    $199–288

  5. Fly Jackson/Vicksburg to Buffalo Niagara International Airport

    1. Fly from Jackson/Vicksburg (JAN) to Buffalo Niagara International Airport (BUF)plane plane JAN - BUF
    5h 52m
    $191–825

  6. Fly Memphis to Rochester, bus

    1. Fly from Memphis (MEM) to Rochester (ROC)plane plane MEM - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 55m
    $241–1,020

  7. Train (Amtrak)

    1. Take the train from Jackson to Chicago Union Stationtrain train City of New Orleans
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    28h 19m
    $420–982

Mississippi to Buffalo by bus

Calendar7Weekly Buses
Duration26h 5mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

Map of how to get from Mississippi to Buffalo.ExpandLaunch map view
  • Distance: 833.2 mi
  • Duration: 5h 6m

What companies run services between Mississippi, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and American Airlines fly from Memphis (MEM) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Jackson to Buffalo via Memphis Bus Station, Nashville Bus Station, and Cleveland Bus Station in around 26h 5m.

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