There are 6 ways to get from Mississippi to Columbia by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Memphis
best- Fly from Memphis (MEM) to Columbia Regional Airport (COU)plane MEM - COU
5h 10m$172–641Bus (Greyhound)
cheapest- Take the bus from Jackson to St Louis Bus Stationbus Greyhound US1173
- Take the bus from St Louis Bus Station to Columbiabus Greyhound US0175s
14h 5m$96–183Train, bus
- Take the train from Jackson to Carbondaletrain
- Take the bus from Carbondale to St. Louisbus
- Take the bus from St Louis Bus Station to Columbiabus
16h 33m$171–371Drive 569.9 mi
- Drive from Jackson to Columbiacar 569.9 mi
10h 10m$104–151Fly from Gulfport-Biloxi Regional Airport
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Columbia Regional Airport (COU)plane GPT - COU
5h 55m$170–676Fly from Jackson/Vicksburg
- Fly from Jackson/Vicksburg (JAN) to Columbia Regional Airport (COU)plane JAN - COU
5h$174–541
Mississippi to Columbia by bus (Greyhound)
Questions & Answers
The cheapest way to get from Mississippi to Columbia is to bus which costs $95 - $190 and takes 14h 5m.
The fastest way to get from Mississippi to Columbia is to fly which takes 5h and costs $170 - $550.
No, there is no direct bus from Mississippi to Columbia. However, there are services departing from Jackson and arriving at Columbia via St Louis Bus Station. The journey, including transfers, takes approximately 14h 5m.
The distance between Mississippi and Columbia is 310 miles. The road distance is 573.2 miles.
The best way to get from Mississippi to Columbia without a car is to bus which takes 14h 5m and costs $95 - $190.
It takes approximately 5h 10m to get from Mississippi to Columbia, including transfers.
Mississippi to Columbia bus services, operated by Greyhound USA, depart from Jackson station.
The best way to get from Mississippi to Columbia is to fly which takes 5h 10m and costs $170 - $650. Alternatively, you can bus, which costs $95 - $190 and takes 14h 5m.
Mississippi to Columbia bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Mississippi to Columbia is 573 miles. It takes approximately 10h 10m to drive from Mississippi to Columbia.
What companies run services between Mississippi, USA and Columbia, MO, USA?
United Airlines and American Airlines fly from Memphis (MEM) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from Jackson to Columbia via St Louis Bus Station in around 14h 5m.
- Website
- aa.com
Flights from Memphis to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Memphis to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $100–550
Flights from Memphis to Columbia Regional Airport via Charlotte
- Ave. Duration
- 6h 15m
- When
- Saturday
- Estimated price
- $130–650
Flights from Gulfport-Biloxi Regional Airport to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 27m
- When
- Every day
- Estimated price
- $110–600
Flights from Gulfport-Biloxi Regional Airport to Columbia Regional Airport via Charlotte
- Ave. Duration
- 9h 21m
- When
- Every day
- Estimated price
- $130–650
Flights from Jackson/Vicksburg to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $85–430
Flights from Jackson/Vicksburg to Columbia Regional Airport via Charlotte
- Ave. Duration
- 5h 54m
- When
- Sunday
- Estimated price
- $110–500
- Website
- united.com
Flights from Memphis to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jackson to Carbondale
- Ave. Duration
- 9h 33m
- Frequency
- Once daily
- Estimated price
- $130–290
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- Greyhound
Bus from St Louis Bus Station to Columbia
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- Greyhound
Bus from St Louis Bus Station to Columbia
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Carbondale to St. Louis
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $14–24
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Mississippi to Columbia bus tickets online with Omio and FlixBus.
There are 50+ hotels available in Columbia.






