There are 6 ways to get from Mississippi to Florence by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Memphis
best- Fly from Memphis (MEM) to Florence Regional Airport (FLO)plane MEM - FLO
4h 22m$117–519Bus (Greyhound)
cheapest- Take the bus from Jackson to Atlanta Bus Stationbus Greyhound US0604
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus Greyhound US0641S / ...
15h 30m$104–202Train (Amtrak)
- Take the train from Jackson to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Greensborotrain
- Take the train from Greensboro to Selma Stationtrain
- Take the train from Selma Station to Florence Stationtrain
33h 12m$414–886Drive 671.3 mi
- Drive from Jackson to Florencecar 671.3 mi
10h 58m$123–177Fly from Gulfport-Biloxi Regional Airport
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Florence Regional Airport (FLO)plane GPT - FLO
4h 22m$110–504Fly from Jackson/Vicksburg
- Fly from Jackson/Vicksburg (JAN) to Florence Regional Airport (FLO)plane JAN - FLO
6h 9m$119–439
Mississippi to Florence by bus (Greyhound)
Questions & Answers
The cheapest way to get from Mississippi to Florence is to bus which costs $100 - $210 and takes 15h 30m.
The fastest way to get from Mississippi to Florence is to fly which takes 4h 22m and costs $110 - $550.
No, there is no direct bus from Mississippi to Florence station. However, there are services departing from Jackson and arriving at Florence Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 15h 30m.
No, there is no direct train from Mississippi to Florence station. However, there are services departing from Jackson and arriving at Florence Station via New Orleans Union Passenger Terminal, Greensboro and Selma Station. The journey, including transfers, takes approximately 33h 12m.
The distance between Mississippi and Florence is 598 miles. The road distance is 675.3 miles.
The best way to get from Mississippi to Florence without a car is to bus which takes 15h 30m and costs $100 - $210.
It takes approximately 4h 22m to get from Mississippi to Florence, including transfers.
Mississippi to Florence bus services, operated by Greyhound USA, depart from Jackson station.
Mississippi to Florence train services, operated by Amtrak, depart from Jackson station.
The best way to get from Mississippi to Florence is to fly which takes 4h 22m and costs $110 - $550. Alternatively, you can bus, which costs $100 - $210 and takes 15h 30m, you could also train, which costs $410 - $900 and takes 33h 12m.
What companies run services between Mississippi, USA and Florence, SC, USA?
American Airlines flies from Memphis (MEM) to Florence Regional Airport (FLO) once daily. Alternatively, you can take a bus from Jackson to Florence Bus Station via Atlanta Bus Station in around 15h 30m.
- Website
- aa.com
Flights from Memphis to Florence Regional Airport via Charlotte
- Ave. Duration
- 4h 32m
- When
- Monday to Saturday
- Estimated price
- $85–480
Flights from Gulfport-Biloxi Regional Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $90–480
Flights from Gulfport-Biloxi Regional Airport to Florence Regional Airport via Dallas/Ft.Worth, Charlotte
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $160–700
Flights from Jackson/Vicksburg to Florence Regional Airport via Charlotte
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $70–380
Flights from Jackson/Vicksburg to Florence Regional Airport via Dallas/Ft.Worth, Charlotte
- Ave. Duration
- 8h 39m
- When
- Every day
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jackson to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h 58m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Greensboro
- Ave. Duration
- 21h 12m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Selma Station
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Train from Selma Station to Florence Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Jackson to Atlanta Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- Twice daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Mississippi to Florence bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Florence is 1h ahead of Mississippi. It is currently 5:34 AM in Mississippi and 6:34 AM in Florence.
Mississippi to Florence train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between Mississippi to Florence is 675 miles. It takes approximately 10h 58m to drive from Mississippi to Florence.
Book your Mississippi to Florence train tickets online with Omio.
Book your Mississippi to Florence bus tickets online with Omio and FlixBus.
There are 49+ hotels available in Florence.





