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How to get fromMississippi to Florida Keysby plane, bus (Greyhound, Flixbus), car, shuttle, bus, or train

Find Transport to Florida Keys

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There are 8 ways to get from Mississippi to Florida Keys by plane, bus (Greyhound, Flixbus), car, shuttle, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Memphis to Key West International Airport

    best
    1. Fly from Memphis (MEM) to Key West International Airport (EYW)plane plane MEM - EYW
    7h 22m
    $184–570

  2. Fly Gulfport-Biloxi Regional Airport to Key West International Airport

    cheapest
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane plane GPT - EYW
    8h 16m
    $167–515

  3. Bus

    1. Take the bus from Jackson to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    28h 50m
    $185–316

  4. Drive  1,028.8 mi

    1. Drive from Jackson to Florida Keyscar car 1,028.8 mi
    18h 28m
    $188–272

  5. Fly Jackson/Vicksburg to Key West International Airport

    1. Fly from Jackson/Vicksburg (JAN) to Key West International Airport (EYW)plane plane JAN - EYW
    7h 18m
    $181–490

  6. Fly Memphis to Miami International Airport, shuttle

    1. Fly from Memphis (MEM) to Miami International Airport (MIA)plane plane MEM - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    8h 6m
    $269–760

  7. Bus to Mobile Regional Airport, fly to Key West International Airport

    1. Take the bus from Biloxi Transit Center to Mobile Bus Stationbus bus
    2. Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane plane MOB - EYW
    9h 13m
    $179–507

  8. Train, bus, shuttle

    1. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Miamibus bus
    4. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    29h 39m
    $369–566

Mississippi to Florida Keys by bus and foot

Calendar14Weekly Services
Duration28h 50mAverage Duration
Ticket$185Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississippi to Florida Keys.ExpandLaunch map view
  • Distance: 903.9 mi
  • Duration: 7h 22m

What companies run services between Mississippi, USA and Florida Keys, FL, USA?

Delta, Allegiant Air, and American Airlines fly from Memphis (MEM) to Key West International Airport (EYW) 3 times a day. Alternatively, you can take a bus from Jackson to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 28h 50m.

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