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How to get fromMississippi to Great Smoky Mountainsby plane, car, or bus

Find Transport to Great Smoky Mountains

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There are 5 ways to get from Mississippi to Great Smoky Mountains by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Memphis, drive

    best
    1. Fly from Memphis (MEM) to Mcghee Tyson Airport (TYS)plane plane MEM - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    3h 14m
    $142–792

  2. Drive 538.3 mi

    cheapest
    1. Drive from Jackson to Great Smoky Mountainscar car 538.3 mi
    10h 2m
    $99–142

  3. Bus, drive (Greyhound)

    1. Take the bus from Jackson to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    21h 3m
    $139–271

  4. Fly from Gulfport-Biloxi Regional Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 37m
    $150–827

  5. Fly from Jackson/Vicksburg, drive

    1. Fly from Jackson/Vicksburg (JAN) to Mcghee Tyson Airport (TYS)plane plane JAN - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 20m
    $149–662

Memphis (MEM) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration2h 37mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from Mississippi to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 407.3 mi
  • Duration: 3h 14m

What companies run services between Mississippi, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Mississippi to Great Smoky Mountains. However, you can take the taxi to Memphis-Airport-MEM airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Jackson to Great Smoky Mountains via Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 21h 3m.

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