Rome2Rio

How to get fromMississippi to Kentuckyby plane, bus, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound)

Find Transport to Kentucky

See all options

There are 6 ways to get from Mississippi to Kentucky by plane, bus, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Memphis, bus

    best
    1. Fly from Memphis (MEM) to Nashville (BNA)plane plane MEM - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    6h 34m
    $109–498

  2. Bus via Nashville

    cheapest
    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    12h 55m
    $94–158

  3. Drive  562.3 mi

    1. Drive from Jackson to Louisvillecar car 562.3 mi
    10h 13m
    $103–149

  4. Fly from Tupelo Regional Airport, bus

    1. Fly from Tupelo Regional Airport (TUP) to Nashville (BNA)plane plane TUP - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    6h 32m
    $102–239

  5. Fly from Jackson/Vicksburg, bus

    1. Fly from Jackson/Vicksburg (JAN) to Nashville (BNA)plane plane JAN - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    6h 57m
    $126–468

  6. Bus

    1. Take the bus from Jackson to Memphis Bus Stationbus bus Greyhound US1173
    2. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus Memphis
    13h 49m
    $136–182

Mississippi to Kentucky by bus

Calendar7Weekly Buses
Duration12h 55mAverage Duration
Ticket$94Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mississippi to Kentucky.ExpandLaunch map view
  • Distance: 391.6 mi
  • Duration: 6h 34m

What companies run services between Mississippi, USA and Kentucky, USA?

You can take a bus from Jackson to Louisville, KY via Memphis Bus Station and Nashville in around 12h 55m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There