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How to get fromMississippi to Knoxvilleby plane, train, bus, taxi, shuttle, or car

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There are 4 ways to get from Mississippi to Knoxville by plane, train, bus, taxi, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Memphis

    best
    1. Fly from Memphis (MEM) to Mcghee Tyson Airport (TYS)plane plane MEM - TYS
    1h 40m
    $197–846

  2. Drive 492.7 mi

    cheapest
    1. Drive from Jackson to Knoxvillecar car 492.7 mi
    8h 4m
    $90–130

  3. Train, bus, taxi, shuttle, drive

    1. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    35h 16m

  4. Fly from Jackson/Vicksburg

    1. Fly from Jackson/Vicksburg (JAN) to Mcghee Tyson Airport (TYS)plane plane JAN - TYS
    3h 45m
    $204–766

Memphis (MEM) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration2h 37mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Mississippi to Knoxville.ExpandLaunch map view
  • Distance: 360.9 mi
  • Duration: 1h 40m

What companies run services between Mississippi, USA and Knoxville, TN, USA?

Allegiant Air, Southwest Airlines, and Delta fly from Memphis (MEM) to Mcghee Tyson Airport (TYS) twice daily.

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