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How to get fromMississippi to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound)

Find Transport to Louisville

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There are 5 ways to get from Mississippi to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Memphis

    best
    1. Fly from Memphis (MEM) to Louisville International Airport (SDF)plane plane MEM - SDF
    4h 27m
    $133–779

  2. Bus via Nashville

    cheapest
    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    12h 55m
    $98–165

  3. Drive  562.3 mi

    1. Drive from Jackson to Louisvillecar car 562.3 mi
    10h 13m
    $103–149

  4. Fly from Jackson/Vicksburg

    1. Fly from Jackson/Vicksburg (JAN) to Louisville International Airport (SDF)plane plane JAN - SDF
    5h 16m
    $140–699

  5. Bus

    1. Take the bus from Jackson to Memphis Bus Stationbus bus Greyhound US1173
    2. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus Memphis
    13h 49m
    $140–184

Mississippi to Louisville by bus

Calendar7Weekly Buses
Duration12h 55mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississippi to Louisville.ExpandLaunch map view
  • Distance: 332.8 mi
  • Duration: 4h 27m

What companies run services between Mississippi, USA and Louisville, KY, USA?

Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Jackson to Louisville, KY via Memphis Bus Station and Nashville in around 12h 55m.

Airlines
Bus operators

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