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How to get fromMississippi to Ohioby plane, bus (Greyhound, Flixbus, Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mississippi to Ohio by plane, bus (Greyhound, Flixbus, Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Memphis (MEM) to Cleveland-Hopkins International Airport (CLE)plane plane MEM - CLE
    4h 8m
    $165–779

  2. Bus via Louisville

    cheapest
    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    4. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus
    18h 15m
    $114–236

  3. Train, bus via Indianapolis

    1. Take the train from Jackson to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Dayton Trotwood Bus Stationbus bus
    4. Take the bus from Dayton Trotwood Bus Station to Columbusbus bus
    21h 15m
    $250–493

  4. Drive 764.6 mi

    1. Drive from Jackson to Columbuscar car 764.6 mi
    13h 40m
    $140–202

  5. Fly to John Glenn Columbus International Airport

    1. Fly from Memphis (MEM) to John Glenn Columbus International Airport (CMH)plane plane MEM - CMH
    4h 26m
    $144–729

  6. Fly to Covington

    1. Fly from Memphis (MEM) to Covington (CVG)plane plane MEM - CVG
    4h 53m
    $135–681

  7. Fly to Detroit, bus

    1. Fly from Memphis (MEM) to Detroit (DTW)plane plane MEM - DTW
    2. Take the bus from Dearborn to Toledobus bus
    5h 27m
    $166–722

  8. Bus

    1. Take the bus from Jackson to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Columbusbus bus
    18h 25m
    $123–246

  9. Train, bus

    1. Take the train from Jackson to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Toledotrain train
    3. Take the bus from Toledo to Columbus - Mound Stbus bus
    24h 24m
    $343–687

Mississippi to Ohio by bus

Calendar7Weekly Buses
Duration18h 15mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from Mississippi to Ohio.ExpandLaunch map view
  • Distance: 641.3 mi
  • Duration: 4h 8m

What companies run services between Mississippi, USA and Ohio, USA?

Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Jackson to Columbus - Downtown - Mound St via Memphis Bus Station, Nashville, and Louisville, KY Bus Station in around 18h 15m.

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Train operators
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