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How to get fromMississippi to Saint Charlesby plane, bus (Greyhound), train, bus, or car

Find Transport to Saint Charles

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There are 5 ways to get from Mississippi to Saint Charles by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Memphis

    best
    1. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)plane plane MEM - STL
    5h 13m
    $142–700

  2. Drive  502.9 mi

    cheapest
    1. Drive from Jackson to Saint Charlescar car 502.9 mi
    8h 10m
    $89–129

  3. Bus (Greyhound)

    1. Take the bus from Jackson to St Louis Bus Stationbus bus Greyhound US1173
    12h 12m
    $112–160

  4. Train, bus

    1. Take the train from Jackson to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    14h 7m
    $278–420

  5. Fly from Jackson/Vicksburg

    1. Fly from Jackson/Vicksburg (JAN) to Lambert–St. Louis International Airport (STL)plane plane JAN - STL
    5h 10m
    $149–620

Memphis (MEM) to Lambert–St. Louis International Airport (STL) flights

Calendar126Weekly Planes
Duration4h 54mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mississippi to Saint Charles.ExpandLaunch map view
  • Distance: 282.8 mi
  • Duration: 5h 13m

What companies run services between Mississippi, USA and Saint Charles, MO, USA?

Delta, Southwest Airlines, and two other airlines fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Jackson to St Louis Bus Station once daily. Tickets cost $90–140 and the journey takes 10h 5m.

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