There are 7 ways to get from Missoula to La Crosse by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to La Crosse
best- Fly from Missoula International Airport (MSO) to La Crosse (LSE)plane MSO - LSE
9h 35m$189–773Fly to Rochester, bus
cheapest- Fly from Missoula International Airport (MSO) to Rochester (RST)plane MSO - RST
- Take the bus from Rochester, MN to La Crossebus
11h 13m$159–680Bus
- Take the bus from Missoula to Billingsbus
- Take the bus from Billings to Minneapolisbus
- Take the bus from Minneapolis Bus Depot to La Crossebus
26h 30m$309–440Bus, train
- Take the bus from Missoula to Spokanebus Jefferson 943 / ...
- Take the train from Spokane to La Crosse Amtrak Stationtrain Empire Builder
37h 17m$553–1,173Drive 1,293.2 mi
- Drive from Missoula to La Crossecar 1,293.2 mi
19h 52m$236–341Fly to Minneapolis–Saint Paul International Airport, train
- Fly from Missoula International Airport (MSO) to Minneapolis–Saint Paul International Airport (MSP)plane MSO - MSP
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
8h 31m$192–838Fly to Dane County Regional Airport-Truax Field, bus
- Fly from Missoula International Airport (MSO) to Dane County Regional Airport-Truax Field (MSN)plane MSO - MSN
- Take the bus from Madison to UW La Crossebus
10h 3m$247–1,007
Missoula International Airport (MSO) to La Crosse (LSE) flights
Questions & Answers
The cheapest way to get from Missoula to La Crosse is to drive which costs $230 - $350 and takes 19h 52m.
The fastest way to get from Missoula to La Crosse is to fly and train which takes 8h 31m and costs $190 - $850.
No, there is no direct bus from Missoula to La Crosse. However, there are services departing from Missoula and arriving at La Crosse via Billings and Minneapolis Bus Depot. The journey, including transfers, takes approximately 26h 30m.
The distance between Missoula and La Crosse is 1146 miles. The road distance is 1300.8 miles.
The best way to get from Missoula to La Crosse without a car is to bus which takes 26h 30m and costs $300 - $440.
It takes approximately 9h 35m to get from Missoula to La Crosse, including transfers.
Missoula to La Crosse bus services, operated by Jefferson Lines, depart from Missoula station.
The best way to get from Missoula to La Crosse is to fly which takes 9h 35m and costs $180 - $800. Alternatively, you can bus, which costs $300 - $440 and takes 26h 30m.
Missoula to La Crosse bus services, operated by Jefferson Lines, arrive at Billings station.
La Crosse is 1h ahead of Missoula. It is currently 8:43 AM in Missoula and 9:43 AM in La Crosse.
What companies run services between Missoula, MT, USA and La Crosse, WI, USA?
American Airlines, Allegiant Air, and two other airlines fly from Missoula International Airport (MSO) to La Crosse (LSE) 5 times a day. Alternatively, you can take a bus from Missoula to La Crosse via Billings, Minneapolis, and Minneapolis Bus Depot in around 26h 30m.
- Website
- united.com
Flights from Missoula International Airport to La Crosse via Denver, Chicago O'Hare
- Ave. Duration
- 14h 32m
- When
- Sunday
- Estimated price
- $190–800
Flights from Missoula International Airport to La Crosse via Las Vegas, Chicago O'Hare
- Ave. Duration
- 10h 4m
- When
- Thursday and Sunday
- Estimated price
- $250–1,000
Flights from Missoula International Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $190–850
Flights from Missoula International Airport to Dane County Regional Airport-Truax Field via Denver
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Missoula International Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- delta.com
Flights from Missoula International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 34m
- When
- Every day
- Estimated price
- $150–750
Flights from Missoula International Airport to Minneapolis–Saint Paul International Airport via Salt Lake City
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $200–850
Flights from Missoula International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $130–600
Flights from Missoula International Airport to Rochester via Salt Lake City, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 9h 34m
- When
- Every day
- Estimated price
- $160–750
Flights from Missoula International Airport to Dane County Regional Airport-Truax Field via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $210–950
- Website
- aa.com
Flights from Missoula International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 10h 33m
- When
- Every day
- Estimated price
- $170–750
Flights from Missoula International Airport to La Crosse via Minneapolis–Saint Paul International Airport, Chicago O'Hare
- Ave. Duration
- 7h 46m
- When
- Every day
- Estimated price
- $170–750
Flights from Missoula International Airport to La Crosse via Denver, Chicago O'Hare
- Ave. Duration
- 8h 42m
- When
- Every day
- Estimated price
- $190–800
Flights from Missoula International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 9h 47m
- When
- Every day
- Estimated price
- $170–750
Flights from Missoula International Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 8h 23m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- allegiantair.com
Flights from Missoula International Airport to La Crosse via Phoenix esa Gateway
- Ave. Duration
- 15h 43m
- When
- Thursday and Sunday
- Estimated price
- $230–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Spokane to La Crosse Amtrak Station
- Ave. Duration
- 32h 22m
- Frequency
- Twice daily
- Estimated price
- $500–1,100
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Missoula to Billings
- Ave. Duration
- 5h 45m
- Frequency
- 4 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from Billings to Minneapolis
- Ave. Duration
- 14h 50m
- Frequency
- Twice daily
- Estimated price
- $180–260
- Book at
- https://www.jeffersonlines.com
- Adult
- $180–260
Bus from Minneapolis Bus Depot to La Crosse
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
Bus from Missoula to Spokane
- Ave. Duration
- 3h 55m
- Frequency
- 4 times a day
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Bus from Rochester, MN to La Crosse
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Madison to UW La Crosse
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Missoula to La Crosse is 1301 miles. It takes approximately 19h 52m to drive from Missoula to La Crosse.
Book your Missoula to La Crosse bus tickets online with Omio.
There are 45+ hotels available in La Crosse.







