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How to get fromMissoula to Louisvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound, Amtrak)

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There are 8 ways to get from Missoula to Louisville by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Missoula International Airport (MSO) to Louisville International Airport (SDF)plane plane MSO - SDF
    8h 35m
    $251–1,103

  2. Bus via Minneapolis

    1. Take the bus from Missoula to Billingsbus bus
    2. Take the bus from Billings to Minneapolisbus bus
    3. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus
    38h 10m
    $374–595

  3. Bus, train

    1. Take the bus from Missoula to Spokanebus bus
    2. Take the train from Spokane to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    2d 3h
    $735–1,548

  4. Drive 1,835.6 mi

    1. Drive from Missoula to Louisvillecar car 1,835.6 mi
    29h 30m
    $335–484

  5. Fly to Blue Grass Airport, drive

    1. Fly from Missoula International Airport (MSO) to Blue Grass Airport (LEX)plane plane MSO - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 50m
    $393–1,619

  6. Fly to Covington, bus

    1. Fly from Missoula International Airport (MSO) to Covington (CVG)plane plane MSO - CVG
    2. Take the bus from Cincinnati to Louisvillebus bus
    11h 11m
    $271–1,147

  7. Fly to Indianapolis, bus

    1. Fly from Missoula International Airport (MSO) to Indianapolis (IND)plane plane MSO - IND
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    11h 12m
    $272–1,163

  8. Bus

    1. Take the bus from Missoula to Billingsbus bus
    2. Take the bus from Billings, MT to Cheyenne, WYbus bus
    3. Take the bus from Cheyenne to Denverbus bus
    4. Take the bus from Denver to Indianapolisbus bus
    5. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    45h 20m

Missoula International Airport (MSO) to Louisville International Airport (SDF) flights

Calendar45Weekly Planes
Duration6h 28mAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

Map of how to get from Missoula to Louisville.ExpandLaunch map view
  • Distance: 1,567.9 mi
  • Duration: 8h 35m

What companies run services between Missoula, MT, USA and Louisville, KY, USA?

United Airlines, American Airlines, and two other airlines fly from Missoula International Airport (MSO) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Missoula to Louisville Bus Station via Billings, Minneapolis Bus Station, and Chicago Bus Station in around 38h 10m.

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