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How to get fromMissouri to Cairoby bus, taxi, train, car, or plane

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There are 5 ways to get from Missouri to Cairo by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 57m
    $137–204

  2. Drive 379.3 mi

    cheapest
    1. Drive from Kansas City to Cairocar car 379.3 mi
    6h 41m
    $70–100

  3. Train, bus, taxi

    1. Take the train from Kansas City to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    10h 43m
    $189–312

  4. Fly from Kansas City, bus, taxi

    1. Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)plane plane MCI - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 32m
    $186–733

  5. Fly to Nashville, bus, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    7h 35m
    $190–620

Kansas City (MCI) to Lambert–St. Louis International Airport (STL) flights

Calendar20Weekly Planes
Duration1h 2mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Cairo.ExpandLaunch map view
  • Distance: 395.7 mi
  • Duration: 7h 57m

What companies run services between Missouri, USA and Cairo, IL, USA?

There is no direct connection from Missouri to Cairo. However, you can take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Cairo. Alternatively, you can take the vehicle to Union Station, walk to Kansas City, take the train to St. Louis, walk to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Cairo.

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