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How to get fromMissouri to Des Moinesby bus (Greyhound), car, or plane

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There are 3 ways to get from Missouri to Des Moines by bus (Greyhound), car, or plane

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  1. Bus

    best
    1. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 804 / ...
    3h 25m
    $28–55

  2. Drive 192 mi

    1. Drive from Kansas City to Des Moinescar car 192 mi
    3h 13m
    $35–51

  3. Fly

    1. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    5h 22m
    $150–774

Missouri to Des Moines by bus

Calendar25Weekly Buses
Duration3h 25mAverage Duration
Ticket$28Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Des Moines.ExpandLaunch map view
  • Distance: 194.3 mi
  • Duration: 3h 25m

What companies run services between Missouri, USA and Des Moines, IA, USA?

Jefferson Lines operates a bus from Kansas City to Des Moines 3 times a day. Tickets cost $50–75 and the journey takes 3h 25m. Greyhound USA also services this route once daily. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) hourly.

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