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How to get fromMissouri to Durhamby plane, bus, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 7 ways to get from Missouri to Durham by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport, bus, line 700 bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane plane STL - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4h 49m
    $558–1,108

  2. Fly from Springfield-Branson National Airport

    cheapest
    1. Fly from Springfield-Branson National Airport (SGF) to Raleigh-Durham International Airport (RDU)plane plane SGF - RDU
    6h 4m
    $122–525

  3. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Durhambus bus
    24h 50m
    $160–326

  4. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    35h 26m
    $400–909

  5. Drive 1,002.5 mi

    1. Drive from Kansas City to Durhamcar car 1,002.5 mi
    17h 53m
    $183–265

  6. Fly from Columbia Regional Airport

    1. Fly from Columbia Regional Airport (COU) to Raleigh-Durham International Airport (RDU)plane plane COU - RDU
    6h 44m
    $156–572

  7. Fly from Kansas City, line 700 bus

    1. Fly from Kansas City (MCI) to Raleigh-Durham International Airport (RDU)plane plane MCI - RDU
    2. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    5h 40m
    $446–1,106

Missouri to Durham by bus

Calendar12Weekly Buses
Duration24h 50mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Durham.ExpandLaunch map view
  • Distance: 696.4 mi
  • Duration: 4h 49m

What companies run services between Missouri, USA and Durham, NC, USA?

You can take a bus from Kansas City Bus Station to Durham via St Louis Bus Station and Atlanta Bus Station in around 24h 50m. Alternatively, you can take a vehicle from Metro Center to Willard St at Durham Station via Union Station, Kansas City, Chicago Union Station, Raleigh Union Station, and Union Station - Bus Platform A in around 35h 26m.

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