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How to get fromMissouri to Florenceby plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

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There are 5 ways to get from Missouri to Florence by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO)plane plane STL - FLO
    6h 13m
    $108–506

  2. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Florencebus bus
    22h 20m
    $169–334

  3. Drive 1,055.7 mi

    1. Drive from Kansas City to Florencecar car 1,055.7 mi
    18h 24m
    $193–279

  4. Fly to Myrtle Beach, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    6h 13m

  5. Bus via New South Memphis

    1. Take the bus from Kansas City to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Sumterbus bus
    4. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    26h 45m

Missouri to Florence by bus

Calendar19Weekly Buses
Duration22h 20mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Florence.ExpandLaunch map view
  • Distance: 685 mi
  • Duration: 6h 13m

What companies run services between Missouri, USA and Florence, SC, USA?

American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Kansas City Bus Station to Florence via St Louis Bus Station and Atlanta in around 22h 20m.

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