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How to get fromMissouri to Greenvilleby plane, bus (Greyhound, Flixbus, Amtrak), car, bus (Greyhound, Flixbus), train, or bus

Find Transport to Greenville

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There are 6 ways to get from Missouri to Greenville by plane, bus (Greyhound, Flixbus, Amtrak), car, bus (Greyhound, Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    4h 59m
    $158–748

  2. Bus via Carbondale

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    21h 10m
    $185–407

  3. Drive 883.7 mi

    1. Drive from Kansas City to Greenvillecar car 883.7 mi
    15h 39m
    $162–233

  4. Fly from Kansas City

    1. Fly from Kansas City (MCI) to Greenville–Spartanburg International Airport (GSP)plane plane MCI - GSP
    5h 50m
    $195–845

  5. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    22h 13m
    $183–405

  6. Train, bus

    1. Take the train from Kansas City to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    24h 41m
    $232–515

Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) flights

Calendar126Weekly Planes
Duration4h 44mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Greenville.ExpandLaunch map view
  • Distance: 549.3 mi
  • Duration: 4h 59m

What companies run services between Missouri, USA and Greenville, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Greenville via St Louis Bus Station, Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 10m.

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