Rome2Rio

How to get fromMissouri to Harrisburgby train, bus, taxi, bus (Greyhound, Flixbus, Amtrak), or car

Find Transport to Harrisburg

See all options

There are 4 ways to get from Missouri to Harrisburg by train, bus, taxi, bus (Greyhound, Flixbus, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus, taxi

    best
    1. Take the train from Kansas City to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Mount Vernonbus bus
    3. Take the taxi from Mount Vernon to Harrisburgtaxi taxi
    10h 16m
    $220–355

  2. Bus

    cheapest
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    10h 24m
    $62–133

  3. Drive 378.1 mi

    1. Drive from Kansas City to Harrisburgcar car 378.1 mi
    6h 36m
    $69–100

  4. Train, bus

    1. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    13h 10m
    $114–246

Questions & Answers

Map of how to get from Missouri to Harrisburg.ExpandLaunch map view
  • Distance: 412.2 mi
  • Duration: 10h 16m

What companies run services between Missouri, USA and Harrisburg, IL, USA?

You can take a bus from Kansas City Bus Station to Harrisburg, IL via St Louis Bus Station, Carbondale,IL - Amtrak, RMTD Park and Ride return, and Marion, IL in around 10h 24m.

Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound