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How to get fromMissouri to Knoxvilleby plane, bus (Greyhound), train, bus, or car

Find Transport to Knoxville

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There are 9 ways to get from Missouri to Knoxville by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Springfield-Branson National Airport to Mcghee Tyson Airport

    best
    1. Fly from Springfield-Branson National Airport (SGF) to Mcghee Tyson Airport (TYS)plane plane SGF - TYS
    4h 18m
    $231–939

  2. Drive  717 mi

    cheapest
    1. Drive from Kansas City to Knoxvillecar car 717 mi
    12h 34m
    $131–189

  3. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    43h 22m
    $382–574

  4. Train, bus

    1. Take the train from Kansas City to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    43h 32m
    $547–1,053

  5. Fly Lambert–St. Louis International Airport to Mcghee Tyson Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    4h 53m
    $198–922

  6. Fly Kansas City to Mcghee Tyson Airport

    1. Fly from Kansas City (MCI) to Mcghee Tyson Airport (TYS)plane plane MCI - TYS
    5h 34m
    $255–1,170

  7. Fly Lambert–St. Louis International Airport to Nashville, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    5h 30m
    $162–802

  8. Train, bus via Galesburg

    1. Take the train from Kansas City to Galesburg Amtrak Stationtrain train
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 15m
    $500–965

  9. Train, bus #2

    1. Take the train from Kansas City to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 41m
    $363–595

Springfield-Branson National Airport (SGF) to Mcghee Tyson Airport (TYS) flights

Calendar124Weekly Planes
Duration5h 4mAverage Duration
Ticket$159Cheapest Price
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Comparing Your Travel Options

Map of how to get from Missouri to Knoxville.ExpandLaunch map view
  • Distance: 551.6 mi
  • Duration: 4h 18m

What companies run services between Missouri, USA and Knoxville, TN, USA?

Delta, American Airlines, and United Airlines fly from Springfield-Branson National Airport (SGF) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Knoxville via St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 43h 22m.

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