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How to get fromMissouri to Lafayetteby plane, shuttle, bus (Greyhound, Amtrak), train, bus, car, or train (Amtrak)

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There are 8 ways to get from Missouri to Lafayette by plane, shuttle, bus (Greyhound, Amtrak), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Kansas City to Indianapolis, shuttle

    best
    1. Fly from Kansas City (MCI) to Indianapolis (IND)plane plane MCI - IND
    2. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    5h 3m
    $614–1,035

  2. Bus

    cheapest
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lafayette Amtrak Stationbus bus
    11h 45m
    $86–185

  3. Train, bus (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    12h 17m
    $162–330

  4. Drive 485.6 mi

    1. Drive from Kansas City to Lafayettecar car 485.6 mi
    8h 19m
    $89–128

  5. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 33m
    $98–460

  6. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 54m
    $310–788

  7. Fly Kansas City to Chicago Midway International Airport, train

    1. Fly from Kansas City (MCI) to Chicago Midway International Airport (MDW)plane plane MCI - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 9m
    $110–518

  8. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    12h 48m
    $174–365

Missouri to Lafayette by bus

Calendar14Weekly Buses
Duration11h 45mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Lafayette.ExpandLaunch map view
  • Distance: 541.3 mi
  • Duration: 5h 3m

What companies run services between Missouri, USA and Lafayette, IN, USA?

You can take a bus from Kansas City Bus Station to Lafayette Amtrak Station via St Louis Bus Station and Indianapolis Union Station in around 11h 45m. Alternatively, you can take a vehicle from Metro Center to Lafayette Amtrak Station via Union Station, Kansas City, and Chicago Union Station in around 12h 48m.

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