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How to get fromMissouri to Louisvilleby plane, bus (Greyhound), train, bus, or car

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There are 5 ways to get from Missouri to Louisville by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    6h 2m
    $104–606

  2. Drive 505.8 mi

    cheapest
    1. Drive from Kansas City to Louisvillecar car 505.8 mi
    8h 26m
    $93–134

  3. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    11h 40m
    $101–179

  4. Train, bus

    1. Take the train from Kansas City to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    14h 26m
    $152–288

  5. Fly from Kansas City

    1. Fly from Kansas City (MCI) to Louisville International Airport (SDF)plane plane MCI - SDF
    6h 23m
    $141–753

Missouri to Louisville by bus

Calendar7Weekly Buses
Duration11h 40mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Louisville.ExpandLaunch map view
  • Distance: 273.1 mi
  • Duration: 6h 2m

What companies run services between Missouri, USA and Louisville, KY, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Louisville, KY via St Louis Bus Station and Evansville, IN in around 11h 40m.

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