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How to get fromMissouri to Panama Cityby plane or car

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There are 7 ways to get from Missouri to Panama City by plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    3h 50m
    $152–562

  2. Fly Lambert–St. Louis International Airport to Pensacola International Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    2. Drive from Pensacola-Airport-PNS to Panama Citycar car
    5h 50m
    $92–432

  3. Drive 934.9 mi

    1. Drive from Kansas City to Panama Citycar car 934.9 mi
    17h 7m
    $171–247

  4. Fly Springfield-Branson National Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Springfield-Branson National Airport (SGF) to Destin–Fort Walton Beach Airport (VPS)plane plane SGF - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    3h 38m
    $93–407

  5. Fly Kansas City to Northwest Florida Beaches International Airport

    1. Fly from Kansas City (MCI) to Northwest Florida Beaches International Airport (ECP)plane plane MCI - ECP
    4h 31m
    $175–680

  6. Fly Lambert–St. Louis International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    4h 51m
    $100–490

  7. Fly Midamerica St. Louis Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    5h 13m
    $102–418

Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP) flights

Calendar31Weekly Planes
Duration2h 57mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Panama City.ExpandLaunch map view
  • Distance: 671.8 mi
  • Duration: 3h 50m

What companies run services between Missouri, USA and Panama City, FL, USA?

Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP) 4 times a day.

Airlines

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