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How to get fromMissouri to Pennsylvaniaby plane, bus (Greyhound), train (Amtrak), car, bus, or train

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There are 8 ways to get from Missouri to Pennsylvania by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Philadelphia International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    4h 27m
    $126–756

  2. Bus (Greyhound)

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    2. Take the bus from St Louis Bus Station to Philadelphia Bus Stationbus bus Greyhound US0421
    27h 25m
    $155–305

  3. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    35h 48m
    $400–909

  4. Drive 1,120.2 mi

    1. Drive from Kansas City to Philadelphiacar car 1,120.2 mi
    19h 4m
    $205–296

  5. Fly Lambert–St. Louis International Airport to Pittsburgh International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Pittsburgh International Airport (PIT)plane plane STL - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    4h 35m

  6. Fly Kansas City to Philadelphia International Airport

    1. Fly from Kansas City (MCI) to Philadelphia International Airport (PHL)plane plane MCI - PHL
    5h 28m
    $403–903

  7. Fly Lambert–St. Louis International Airport to Baltimore-Washington International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    5h 56m
    $140–1,258

  8. Fly Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    2. Take the bus from Cleveland Bus Station to Eriebus bus
    6h 15m
    $510–936

Missouri to Pennsylvania by bus (Greyhound)

Calendar21Weekly Buses
Duration27h 25mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Pennsylvania.ExpandLaunch map view
  • Distance: 833.7 mi
  • Duration: 4h 27m

What companies run services between Missouri, USA and Pennsylvania, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL) every 4 hours. Alternatively, you can take a bus from Kansas City Bus Station to Philadelphia Bus Station via St Louis Bus Station in around 27h 25m.

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