There are 10 ways to get from Missouri to Pennsylvania by plane, bus, bus (Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Lambert–St. Louis International Airport to Pittsburgh International Airport, bus
best- Fly from Lambert–St. Louis International Airport (STL) to Pittsburgh International Airport (PIT)plane STL - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
4h 34mFly Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport, bus
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane STL - CLE
- Take the bus from Cleveland Bus Station to Eriebus
6h 15m$120–590Bus (Greyhound)
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0180s / ...
- Take the bus from St Louis Bus Station to Philadelphia Bus Stationbus Greyhound US0421
27h 25m$206–317Train (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the train from Chicago Union Station to 30th Street Stationtrain Cardinal
35h 48m$792–1,272Drive 1,120.2 mi
- Drive from Kansas City to Philadelphiacar 1,120.2 mi
19h 3m$198–286Fly Lambert–St. Louis International Airport to Philadelphia International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane STL - PHL
4h 27m$124–756Fly Kansas City to Philadelphia International Airport
- Fly from Kansas City (MCI) to Philadelphia International Airport (PHL)plane MCI - PHL
5h 18m$152–754Fly Lambert–St. Louis International Airport to Baltimore-Washington International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane STL - BWI
- Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
5h 46m$128–1,208Fly Lambert–St. Louis International Airport to Newark Liberty International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane STL - EWR
- Take the train from Newark Liberty International Airport to 30th Street Stationtrain
6h 18m$334–976Train, bus
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the bus from Chicago Bus Station to Philadelphia Bus Stationbus FlixBus N2642
30h 6m$380–588
Missouri to Pennsylvania by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Missouri to Pennsylvania is to fly which costs $120 - $800 and takes 4h 27m.
The fastest way to get from Missouri to Pennsylvania is to fly which takes 4h 27m and costs $120 - $800.
No, there is no direct bus from Missouri station to Pennsylvania station. However, there are services departing from Kansas City Bus Station and arriving at Philadelphia Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 27h 25m.
No, there is no direct train from Missouri to Pennsylvania. However, there are services departing from Metro Center and arriving at 15th St/City Hall via Kansas City, Chicago Union Station and Drexel Station at 30th St. The journey, including transfers, takes approximately 35h 48m.
The distance between Missouri and Pennsylvania is 594 miles. The road distance is 1126.7 miles.
The best way to get from Missouri to Pennsylvania without a car is to bus which takes 27h 25m and costs $200 - $320.
It takes approximately 4h 34m to get from Missouri to Pennsylvania, including transfers.
Missouri to Pennsylvania bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
Missouri to Pennsylvania train services, operated by Amtrak, depart from Kansas City station.
The best way to get from Missouri to Pennsylvania is to bus which takes 27h 25m and costs $200 - $320. Alternatively, you can train, which costs $750 - $1,300 and takes 35h 48m, you could also fly, which costs $120 - $800 and takes 4h 27m.
What companies run services between Missouri, USA and Pennsylvania, USA?
You can take a bus from Kansas City Bus Station to Philadelphia Bus Station via St Louis Bus Station in around 27h 25m. Alternatively, you can take a vehicle from Metro Center to 15th St/City Hall via Union Station, Kansas City, Chicago Union Station, 30Th Street Station, and Drexel Station at 30th St in around 35h 48m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $95–600
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Chicago Midway
- Ave. Duration
- 3h 36m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Nashville
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Lambert–St. Louis International Airport to Philadelphia International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Philadelphia International Airport via Chicago Midway
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $120–650
Flights from Lambert–St. Louis International Airport to Philadelphia International Airport via Baltimore-Washington International Airport
- Ave. Duration
- 4h 30m
- When
- Monday to Friday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Philadelphia International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $120–650
Flights from Kansas City to Philadelphia International Airport via Chicago Midway
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $150–800
Flights from Kansas City to Philadelphia International Airport via Baltimore-Washington International Airport
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–750
Flights from Kansas City to Philadelphia International Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Baltimore-Washington International Airport via Chicago Midway
- Ave. Duration
- 4h 6m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Baltimore-Washington International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Friday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $95–550
Flights from Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport via Chicago Midway
- Ave. Duration
- 3h 30m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport via Nashville
- Ave. Duration
- 3h 37m
- When
- Thursday to Wednesday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $100–600
Flights from Kansas City to Philadelphia International Airport via Detroit
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $150–800
Flights from Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $95–600
Flights from Lambert–St. Louis International Airport to Newark Liberty International Airport via Detroit
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $85–430
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Newark Liberty International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $80–420
Flights from Lambert–St. Louis International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $80–430
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Philadelphia International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $110–600
Flights from Kansas City to Philadelphia International Airport
- Ave. Duration
- 2h 42m
- When
- Every day
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Chicago Union Station to 30th Street Station
- Ave. Duration
- 25h 56m
- Frequency
- 3 times a week
- Estimated price
- $550–900
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Newark Liberty International Airport to 30th Street Station
- Ave. Duration
- 1h 3m
- Frequency
- Every 2 hours
- Estimated price
- $40–70
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Philadelphia Bus Station
- Ave. Duration
- 22h 25m
- Frequency
- 3 times a day
- Estimated price
- $160–250
- Website
- Greyhound
Bus from Cleveland Bus Station to Erie
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Philadelphia Bus Station
- Ave. Duration
- 20h 10m
- Frequency
- 4 times a week
- Estimated price
- $140–220
- Schedules at
- Flixbus USA
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Booking & Getting There
Missouri to Pennsylvania bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Pennsylvania is 1h ahead of Missouri. It is currently 7:59 AM in Missouri and 8:59 AM in Pennsylvania.
Missouri to Pennsylvania train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Missouri to Pennsylvania is 1127 miles. It takes approximately 19h 3m to drive from Missouri to Pennsylvania.
Book your Missouri to Pennsylvania bus tickets online with Omio and FlixBus.
There are 943+ hotels available in Pennsylvania.









