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How to get fromMissouri to Sioux Fallsby bus (Greyhound), car, plane, or bus

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There are 7 ways to get from Missouri to Sioux Falls by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Des Moines

    best
    1. Take the bus from Kansas City to Des Moinesbus bus
    2. Take the bus from Des Moines to Omaha, NEbus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    11h 19m
    $117–197

  2. Drive 359.8 mi

    cheapest
    1. Drive from Kansas City to Sioux Fallscar car 359.8 mi
    5h 47m
    $66–95

  3. Fly from Columbia Regional Airport

    1. Fly from Columbia Regional Airport (COU) to Sioux Falls (FSD)plane plane COU - FSD
    6h 51m
    $137–468

  4. Bus

    1. Take the bus from 2745 Southwest Blvd - Kansas City to Quincy Street Station - Topekabus bus
    2. Take the bus from Topeka to Omahabus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    13h 51m
    $255–300

  5. Fly from Springfield-Branson National Airport

    1. Fly from Springfield-Branson National Airport (SGF) to Sioux Falls (FSD)plane plane SGF - FSD
    6h 17m
    $103–451

  6. Fly from Lambert–St. Louis International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane plane STL - FSD
    6h 39m
    $94–494

  7. Fly from Kansas City

    1. Fly from Kansas City (MCI) to Sioux Falls (FSD)plane plane MCI - FSD
    6h 40m
    $97–502

Columbia Regional Airport (COU) to Sioux Falls (FSD) flights

Calendar56Weekly Planes
Duration6h 40mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Missouri to Sioux Falls.ExpandLaunch map view
  • Distance: 530.9 mi
  • Duration: 11h 19m

What companies run services between Missouri, USA and Sioux Falls, SD, USA?

You can take a bus from Kansas City to Sioux Falls via Des Moines, Omaha, and Sioux Falls in around 11h 19m. Alternatively, American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Sioux Falls (FSD) every 4 hours.

Airlines
Bus operators

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