There are 8 ways to get from Missouri to West Lafayette by plane, bus, train, bus (Greyhound), car, shuttle, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Kansas City to Indianapolis, bus
best- Fly from Kansas City (MCI) to Indianapolis (IND)plane MCI - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
5h 27m$138–740Drive 484.9 mi
cheapest- Drive from Kansas City to West Lafayettecar 484.9 mi
8h 17m$86–124Train, bus (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus Chicago
12h 7m$263–413Bus (Greyhound)
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus
12h 20m$102–155Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, shuttle
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
- Take a shuttle bus from O'Hare International Terminal 2 to West Lafayette, IN
7h 36m$354–764Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
7h 29m$124–518Fly Kansas City to Chicago Midway International Airport, train
- Fly from Kansas City (MCI) to Chicago Midway International Airport (MDW)plane MCI - MDW
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
8h 5m$147–615Train (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain Southwest Chief / ...
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain Cardinal
12h 48m$305–478
Missouri to West Lafayette by tram, train, and bus (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Missouri to West Lafayette is to drive which costs $85 - $130 and takes 8h 17m.
The fastest way to get from Missouri to West Lafayette is to fly and bus which takes 5h 27m and costs $130 - $750.
No, there is no direct bus from Missouri station to West Lafayette. However, there are services departing from Kansas City Bus Station and arriving at Lafayette Bus Stop via St Louis Bus Station and Indianapolis Union Station. The journey, including transfers, takes approximately 12h 20m.
No, there is no direct train from Missouri to West Lafayette station. However, there are services departing from Metro Center and arriving at Lafayette Amtrak Station via Kansas City and Chicago Union Station. The journey, including transfers, takes approximately 12h 48m.
The distance between Missouri and West Lafayette is 546 miles. The road distance is 487.7 miles.
The best way to get from Missouri to West Lafayette without a car is to train and bus which takes 12h 7m and costs $260 - $420.
It takes approximately 5h 27m to get from Missouri to West Lafayette, including transfers.
Missouri to West Lafayette bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
Missouri to West Lafayette train services, operated by Amtrak, depart from Kansas City station.
The best way to get from Missouri to West Lafayette is to bus which takes 12h 20m and costs $100 - $160. Alternatively, you can train, which costs $300 - $480 and takes 12h 48m.
What companies run services between Missouri, USA and West Lafayette, IN, USA?
You can take a bus from Kansas City Bus Station to Lafayette Bus Stop via St Louis Bus Station and Indianapolis Union Station in around 12h 20m. Alternatively, you can take a vehicle from Metro Center to Lafayette Amtrak Station via Union Station, Kansas City, and Chicago Union Station in around 12h 48m.
- Website
- southwest.com
Flights from Kansas City to Indianapolis
- Ave. Duration
- 1h 22m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
Flights from Kansas City to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 3h 27m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $55–400
Flights from Kansas City to Chicago Midway International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $80–500
Flights from Kansas City to Chicago Midway International Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $90–550
Flights from Kansas City to Chicago Midway International Airport via Milwaukee
- Ave. Duration
- 3h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $90–550
Flights from Kansas City to Chicago Midway International Airport via Indianapolis
- Ave. Duration
- 3h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $100–600
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–290
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $40–290
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–290
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
- Phone
- +1 765-637-5124
- [email protected]
- Website
- Reindeer Shuttle
Bus from Indianapolis Airport to Purdue Memorial Union
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–36
- Website
- Reindeer Shuttle
- Online Advance
- $28–31
- Walk up Cash
- $33–36
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $23–45
- Website
- Amtrak
- Adult
- $23–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Indianapolis Union Station to Lafayette Bus Stop
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $11–18
- Website
- Greyhound
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from O'Hare International Terminal 2 to West Lafayette, IN
- Ave. Duration
- 3h 51m
- Frequency
- On demand
- Estimated price
- $30–56
- Schedules at
- lafayettelimo.com
- Child
- $30–50
- Adult
- $51–56
Want to know more about travelling around United States
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Booking & Getting There
Missouri to West Lafayette bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
West Lafayette is 1h ahead of Missouri. It is currently 1:12 AM in Missouri and 2:12 AM in West Lafayette.
Missouri to West Lafayette train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Missouri to West Lafayette is 488 miles. It takes approximately 8h 17m to drive from Missouri to West Lafayette.
Book your Missouri to West Lafayette bus tickets online with Omio and FlixBus.
There are 51+ hotels available in West Lafayette.










