There are 10 ways to get from Missouri to Winston-Salem by plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound, Flixbus, Amtrak), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Lambert–St. Louis International Airport to Piedmont Triad International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO)plane STL - GSO
6h 17m$102–486Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
22h 30m$186–307Drive 925.4 mi
- Drive from Kansas City to Winston-Salemcar 925.4 mi
16h 37m$164–237Fly Springfield-Branson National Airport to Charlotte Douglas International Airport, bus
- Fly from Springfield-Branson National Airport (SGF) to Charlotte Douglas International Airport (CLT)plane SGF - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 39m$144–696Fly Columbia Regional Airport to Charlotte Douglas International Airport, bus
- Fly from Columbia Regional Airport (COU) to Charlotte Douglas International Airport (CLT)plane COU - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 41m$183–743Fly Lambert–St. Louis International Airport to Charlotte Douglas International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane STL - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 23m$140–780Fly Kansas City to Charlotte Douglas International Airport, bus
- Fly from Kansas City (MCI) to Charlotte Douglas International Airport (CLT)plane MCI - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
7h 22m$188–977Fly Lambert–St. Louis International Airport to Raleigh-Durham International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane STL - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
7h 36m$132–680Bus via Carbondale
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Downtown to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
23h 49m$183–284Train, bus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
25h 16m$293–475
Missouri to Winston-Salem by bus
Comparing Your Travel Options
The cheapest way to get from Missouri to Winston-Salem is to drive which costs $160 - $240 and takes 16h 37m.
The fastest way to get from Missouri to Winston-Salem is to fly and bus which takes 5h 39m and costs $140 - $700.
No, there is no direct bus from Missouri station to Winston-Salem. However, there are services departing from Kansas City Bus Station and arriving at Winston Salem(Trans Center) via St Louis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 22h 30m.
The distance between Missouri and Winston-Salem is 641 miles. The road distance is 930.8 miles.
The best way to get from Missouri to Winston-Salem without a car is to bus which takes 22h 30m and costs $180 - $310.
It takes approximately 6h 17m to get from Missouri to Winston-Salem, including transfers.
Missouri to Winston-Salem bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
The best way to get from Missouri to Winston-Salem is to fly which takes 6h 17m and costs $100 - $490. Alternatively, you can bus, which costs $180 - $310 and takes 22h 30m.
Missouri to Winston-Salem bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Winston-Salem is 1h ahead of Missouri. It is currently 2:08 PM in Missouri and 3:08 PM in Winston-Salem.
What companies run services between Missouri, USA and Winston-Salem, NC, USA?
American Airlines, Delta, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Winston Salem(Trans Center) via St Louis Bus Station and Atlanta Bus Station in around 22h 30m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $80–460
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 7h 19m
- When
- Sunday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 8h 15m
- When
- Every day
- Estimated price
- $120–600
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $110–650
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $150–750
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $170–800
Flights from Columbia Regional Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $110–650
Flights from Columbia Regional Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $120–750
Flights from Kansas City to Charlotte Douglas International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $170–950
Flights from Lambert–St. Louis International Airport to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $120–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $90–490
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $100–550
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 6m
- When
- Sunday
- Estimated price
- $140–750
Flights from Kansas City to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Lambert–St. Louis International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 42m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Kansas City to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–950
Flights from Kansas City to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Kansas City to Charlotte Douglas International Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $170–950
Flights from Lambert–St. Louis International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $110–650
Flights from Lambert–St. Louis International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 47m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Lambert–St. Louis International Airport to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–700
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $100–550
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $150–750
Flights from Columbia Regional Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $100–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $14–21
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $100–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $55–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- 5 times a week
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Bus from Atlanta Downtown to Charlotte Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 4 times a week
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
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Booking & Getting There
Yes, the driving distance between Missouri to Winston-Salem is 931 miles. It takes approximately 16h 37m to drive from Missouri to Winston-Salem.
Book your Missouri to Winston-Salem bus tickets online with Omio and FlixBus.
There are 152+ hotels available in Winston-Salem.








