There are 11 ways to get from Missouri to Winston-Salem by plane, bus (Greyhound, Amtrak, Flixbus), train (Amtrak), car, bus, bus (Greyhound, Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Lambert–St. Louis International Airport to Piedmont Triad International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO)plane STL - GSO
6h 22m$182–926Fly Lambert–St. Louis International Airport to Charlotte Douglas International Airport, bus
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane STL - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 34m$124–698Bus via Carbondale
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St. Louis to Carbondalebus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Downtown to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
23h 49m$163–299Train (Amtrak)
- Take the train from Kansas City to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carytrain
- Take the train from Cary to High Pointtrain
38h 35m$417–954Drive 925.5 mi
- Drive from Kansas City to Winston-Salemcar 925.5 mi
16h 31m$169–244Fly Springfield-Branson National Airport to Charlotte Douglas International Airport, bus
- Fly from Springfield-Branson National Airport (SGF) to Charlotte Douglas International Airport (CLT)plane SGF - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 41m$127–665Fly Columbia Regional Airport to Charlotte Douglas International Airport, bus
- Fly from Columbia Regional Airport (COU) to Charlotte Douglas International Airport (CLT)plane COU - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 44m$166–662Fly Kansas City to Charlotte Douglas International Airport, bus
- Fly from Kansas City (MCI) to Charlotte Douglas International Airport (CLT)plane MCI - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
7h 24m$161–846Fly Lambert–St. Louis International Airport to Raleigh-Durham International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane STL - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
7h 36m$570–1,128Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
24h$169–281Train, bus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
26h 46m$202–379
Missouri to Winston-Salem by bus and subway
Comparing Your Travel Options
The cheapest way to get from Missouri to Winston-Salem is to bus which costs $160 - $290 and takes 24h.
The fastest way to get from Missouri to Winston-Salem is to fly and bus which takes 5h 41m and costs $120 - $700.
No, there is no direct bus from Missouri station to Winston-Salem. However, there are services departing from Kansas City Bus Station and arriving at Winston Salem(Trans Center) via St. Louis, Carbondale Intermodal Station, Atlanta Downtown and Charlotte Bus Station. The journey, including transfers, takes approximately 23h 49m.
No, there is no direct train from Missouri to Winston-Salem. However, there are services departing from Metro Center and arriving at High Point via Kansas City, Chicago Union Station and Cary. The journey, including transfers, takes approximately 38h 35m.
The distance between Missouri and Winston-Salem is 641 miles. The road distance is 930.9 miles.
The best way to get from Missouri to Winston-Salem without a car is to bus via Carbondale which takes 23h 49m and costs $160 - $300.
It takes approximately 6h 22m to get from Missouri to Winston-Salem, including transfers.
Missouri to Winston-Salem bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
Missouri to Winston-Salem train services, operated by Amtrak, depart from Kansas City station.
The best way to get from Missouri to Winston-Salem is to fly which takes 6h 22m and costs $180 - $950. Alternatively, you can bus via Carbondale, which costs $160 - $300 and takes 23h 49m, you could also train, which costs $410 - $1,000 and takes 38h 35m.
What companies run services between Missouri, USA and Winston-Salem, NC, USA?
Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Winston Salem(Trans Center) via St Louis Bus Station, St. Louis, Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, Atlanta Downtown, and Charlotte Bus Station in around 23h 49m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $160–900
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $180–950
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Lambert–St. Louis International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $100–600
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $160–750
Flights from Springfield-Branson National Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $130–700
Flights from Columbia Regional Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $100–550
Flights from Columbia Regional Airport to Charlotte Douglas International Airport via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $120–650
Flights from Lambert–St. Louis International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $110–650
Flights from Kansas City to Charlotte Douglas International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $110–250
- Website
- Amtrak
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $280–650
- Website
- Amtrak
Train from Cary to High Point
- Ave. Duration
- 1h 39m
- Frequency
- 4 times a day
- Estimated price
- $22–50
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $70–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–65
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $12–20
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–65
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
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Booking & Getting There
Missouri to Winston-Salem bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Winston-Salem is 1h ahead of Missouri. It is currently 5:41 AM in Missouri and 6:41 AM in Winston-Salem.
Missouri to Winston-Salem train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Missouri to Winston-Salem is 931 miles. It takes approximately 16h 31m to drive from Missouri to Winston-Salem.
Book your Missouri to Winston-Salem bus tickets online with Omio and FlixBus.
There are 145+ hotels available in Winston-Salem.







