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How to get fromMobile to Buffaloby plane, bus (Greyhound), train (Amtrak), car, bus, train, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Mobile to Buffalo by plane, bus (Greyhound), train (Amtrak), car, bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF)plane plane MOB - BUF
    5h 30m
    $164–739

  2. Fly Mobile Regional Airport to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Toronto Pearson International Airport (YYZ)plane plane MOB - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    9h 16m
    $126–480

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Clevelandbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    30h 28m
    $186–357

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    36h 57m
    $372–1,079

  5. Drive  1,125.9 mi

    1. Drive from Mobile to Buffalocar car 1,125.9 mi
    19h 58m
    $206–297

  6. Fly Mobile Regional Airport to Rochester, bus

    1. Fly from Mobile Regional Airport (MOB) to Rochester (ROC)plane plane MOB - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 24m
    $241–978

  7. Train to Gulfport-Biloxi Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Buffalo Niagara International Airport (BUF)plane plane GPT - BUF
    8h 34m
    $174–812

  8. Bus via Akron

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    3. Take the bus from Toledo Bus Stop to Robert K Pfaff Transit Center - Akronbus bus
    4. Take the bus from Akron to Buffalobus bus
    32h 31m
    $200–352

Mobile to Buffalo by bus

Calendar7Weekly Buses
Duration30h 28mAverage Duration
Ticket$186Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mobile to Buffalo.ExpandLaunch map view
  • Distance: 1,020.8 mi
  • Duration: 5h 30m

What companies run services between Mobile, AL, USA and Buffalo, NY, USA?

Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Govt WB and Joachim St to Buffalo, NY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Toledo, and Cleveland, OH in around 30h 28m.

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