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How to get fromMobile to Charlestonby plane, bus (Greyhound), car, train, or bus

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There are 7 ways to get from Mobile to Charleston by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mobile Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Charleston International Airport (CHS)plane plane MOB - CHS
    8h 48m
    $73–380

  2. Bus

    1. Take the bus from Mobile Bus Station to Atlanta Bus Stationbus bus Greyhound US0602 / ...
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    21h 21m
    $155–255

  3. Drive 578.9 mi

    1. Drive from Mobile to Charlestoncar car 578.9 mi
    10h 49m
    $106–153

  4. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Charleston International Airport (CHS)plane plane GPT - CHS
    8h 24m
    $130–557

  5. Bus to Destin–Fort Walton Beach Airport, fly

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS)plane plane VPS - CHS
    8h 29m
    $166–498

  6. Bus to Pensacola International Airport, fly

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Charleston International Airport (CHS)plane plane PNS - CHS
    9h
    $372–1,220

  7. Train to Louis Armstrong New Orleans International Airport, fly

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Charleston International Airport (CHS)plane plane MSY - CHS
    9h 29m
    $134–576

Mobile to Charleston by bus

Calendar7Weekly Buses
Duration21h 21mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Charleston.ExpandLaunch map view
  • Distance: 542.1 mi
  • Duration: 8h 48m

What companies run services between Mobile, AL, USA and Charleston, SC, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Charleston International Airport (CHS) every 4 hours. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Transit Mall via Govt WB Across from Greyhound, Mobile Bus Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 21h 21m.

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